Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.070 GeneticVariation BEFREE Minor allele frequencies (C allele) of the MnSOD Val16Ala polymorphism (rs4880) in the normal glucose tolerance (NGT) and the T2D</span> groups were 13.57% and 14.50%, respectively. 27258818 2016
Diabetes Mellitus, Non-Insulin-Dependent
0.070 GeneticVariation BEFREE Haplotype/gene-gene interaction analysis in controls and cases showed that SOD2 + 47C/T and GPx1 + 599C/T were in linkage disequilibrium (D: 0.168; r(2): 0.10) and individuals with this combination had a 1.273 times higher risk [OR; CI (95%)] of developing T2DM. 25283363 2015
Diabetes Mellitus, Non-Insulin-Dependent
0.070 GeneticVariation BEFREE To evaluate whether the genetic polymorphisms of glutathione S-transferases M1 (GSTM1) and T1 (GSTT1), Ile105Val of the GSTP1 (rs947894), and the Val16Ala polymorphism of the MnSOD (rs4880) are associated with essential arterial hypertension (EAH) in Caucasians with type 2 diabetes. 24685594 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.070 GeneticVariation BEFREE SOD2 gene Val16Ala polymorphism is associated with macroalbuminuria in Mexican type 2 diabetes patients: a comparative study and meta-analysis. 24119114 2013
Diabetes Mellitus, Non-Insulin-Dependent
0.070 GeneticVariation BEFREE We may conclude that the VV genotype of the V16A polymorphism of the Mn-SOD gene was associated with diabetic retinopathy in Caucasians with type 2 diabetes, therefore it might be used as a genetic marker of diabetic retinopathy in Caucasians. 18057537 2008
Diabetes Mellitus, Non-Insulin-Dependent
0.070 GeneticVariation BEFREE These results suggest that V16A polymorphism of Mn-SOD gene is not related to pathogenesis of diabetes but is associated with stages of albuminuria in Korean type 2 diabetes. 16324912 2006
Diabetes Mellitus, Non-Insulin-Dependent
0.070 GeneticVariation BEFREE This study was designed to investigate whether V16A polymorphism of the manganese superoxide dismutase (Mn-SOD) gene is associated with the development of type 2 diabetes mellitus and with progression of diabetic retinopathy (DR) and diabetic macular edema (DME). 17142144 2006