rs4986790, TLR4

N. diseases: 223
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.080 GeneticVariation BEFREE No association between rs4986790 and CAD risk was found. 30784241 2019
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.080 GeneticVariation BEFREE Association between Toll-like receptor 4 Asp299Gly polymorphism and coronary heart disease susceptibility. 28793055 2017
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.080 GeneticVariation BEFREE No association between TLR2-Arg677Trp or TLR4-Asp299Gly and -Thr399Ile gene polymorphisms and the presence or the severity of CAD was observed. 25542811 2015
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.080 GeneticVariation BEFREE TLR4 gene polymorphism (Asp299Gly) attenuates innate immune responsiveness, reduces the risk for coronary artery disease, and increases a chance of longevity. 19273219 2009
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.080 GeneticVariation BEFREE We studied the TLR4 gene Asp299Gly polymorphism in relation to susceptibility to myocardial infarction in a cohort of patients with angiographically documented coronary artery disease, and performed a meta-analysis using data sets from three independent studies. 15864121 2005
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.080 GeneticVariation BEFREE Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. 15632890 2004
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.080 GeneticVariation BEFREE Among symptomatic men with documented coronary artery disease, the TLR4 Asp299Gly polymorphism was associated with the risk of cardiovascular events. 12742999 2003
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.080 GeneticVariation BEFREE The findings of this study do not support the hypothesis that the TLR4 Asp299Gly polymorphism influences predisposition to and progression of coronary artery disease. 12957699 2003