rs5443, CDCA3;GNB3

N. diseases: 106
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.060 GeneticVariation BEFREE A case-control association study (225 healthy adults and 188 outpatients with depression) was performed to establish Risk-Combined Genotype (RCG) of the studied variants (OXTR rs53576 and the functional Gβ3 subunit rs5443). 28499211 2017
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.060 GeneticVariation BEFREE The GNB3 C825T polymorphism as a pharmacogenetic marker in the treatment of hypertension, obesity, and depression. 21709600 2011
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.060 GeneticVariation BEFREE The GNB3 C825T polymorphism and depression among subjects with alcohol dependence. 16897596 2007
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.060 GeneticVariation BEFREE Serotonin 2A -1438 G/A and G-protein Beta3 subunit C825T polymorphisms in patients with depression and SSRI-associated sexual side-effects. 16710319 2006
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.060 GeneticVariation BEFREE In patients with functional dyspepsia, altered alpha-adrenoreceptor function and depression are prevalent, features that are linked to a G-protein beta 3 (GNB3) subunit gene polymorphism (C825T). 15057736 2004
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.060 GeneticVariation BEFREE A C825T polymorphism of a gene encoding the beta3 subunit of heterotrimeric G proteins (GNB3) was reported to be associated with several pathological conditions, such as hypertension and depressive disorder. 12075862 2002