rs5443, CDCA3;GNB3

N. diseases: 106
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Erectile dysfunction
CUI: C0242350
Disease: Erectile dysfunction
0.040 GeneticVariation BEFREE The insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme gene (ACE) and the C825T polymorphism in the G-protein β3 subunit gene (GNB3) are associated with the efficacy of phosphodiesterase-5 inhibitor (PDE-5I) in erectile dysfunction. 26821322 2016
Erectile dysfunction
CUI: C0242350
Disease: Erectile dysfunction
0.040 GeneticVariation BEFREE In contrast to the previous studies in this analysis, the risk to develop ED is not influenced by the genotypes in the GNB3 C825T, the ACE I/D and the eNOS G894T polymorphisms. 20629643 2010
Erectile dysfunction
CUI: C0242350
Disease: Erectile dysfunction
0.040 GeneticVariation BEFREE Our results failed to show a significant association of the GNB3 C825T polymorphisms with ED prevalence. 18783529 2008
Erectile dysfunction
CUI: C0242350
Disease: Erectile dysfunction
0.040 GeneticVariation BEFREE The response to sildenafil is significantly associated with GNB3 C825T genotype status in patients with erectile dysfunction. 12576843 2003