rs5498, ICAM4;ICAM1

N. diseases: 99
Disease: Coronary Artery Disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE In conclusion, this meta-analysis indicates that ICAM-1 gene rs5498 polymorphism decreases the risk of CAD. 30290609 2018
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE Therefore, we conducted a study to associate the single nucleotide polymorphisms (SNPs) of ICAM-1, rs5491, rs5498, rs281432 and rs3093030 with CAD. 26078712 2015
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE In conclusion, this meta-analysis suggested that the ICAM-1 K469E polymorphism was a risk factor for CAD. 25025994 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE Overall, a significant association between ICAM-1 K469E polymorphism and CAD was observed in the dominant model (OR=1.80; 95% CI 1.62-2.01; P<0.00001; Pheterogeneity=0.40). 25503951 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE The K allele of the ICAM-1 E469K gene might predispose to the CAD susceptibility. 21987404 2012
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE There is a synergistic interaction between rs5498 genotype and smoking that increases the risk of CAD. 19048183 2009