rs6265, BDNF;BDNF-AS

N. diseases: 272
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE Trend level gene-gender interaction effect for the BDNF rs6265 variant on age of onset of psychosis. 31445421 2019
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE The BDNF-Val66Met polymorphism may index susceptibility to expression of psychosis along a spectrum. 29785763 2019
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome. 31822818 2019
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE This study suggests that the common Val66Met polymorphism of the BDNF gene may modulate the relationship between life stress and calorie intake in subjects at risk for psychosis. 27629407 2018
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE These findings provide evidence of the important role of early cannabis use and the Val66Met BDNF polymorphism on age at psychosis onset and they point out to sex-specific differences in cannabis use patterns. 28142064 2017
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE One of the most studied genetic phenotypes for psychosis is brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms. 26603624 2016
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE The present findings indicate that rs6265 is associated with METH dependence in the Thai population, with the GG genotype greater in METH-dependent subjects but reducing the emergence of METH-dependent psychosis. 26401760 2015
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE Further, our study supports a two hit model including a history of childhood trauma as well as genetic vulnerability (met carriers of the BDNF val66met) behind reduced volume of hippocampal subfields in psychosis. 25246365 2014
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE The present study aimed to explore possible effects of BDNF Val66Met polymorphism variations on progressive structural brain changes after 3 years from the first episode of psychosis. 23748016 2013
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE Results suggest the effects of the BDNF Val66Met allele may be different in patients with psychosis than in healthy adults. 22192502 2012
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE We performed BDNF val66met variant genotyping, cognitive testing (verbal fluency and digit spans) and assessments of symptom severity (as assessed with the PANSS) in a population-based sample of FEP patients (77 with schizophreniform psychosis and 53 with affective psychoses) and 191 neighboring healthy controls. 23429848 2012
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE The results had adequate statistical power to suggest that BDNF Val66Met was not related to susceptibility to AD or the onset of AD, but that presence of one or two Met alleles of BDNF Val66Met polymorphism might present a risk factor for psychosis in AD. 21044653 2011
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE We performed a family-based association study and ETDT analyses of the Val66Met polymorphism in nuclear families with at least one subject affected by major psychosis with suicidal behaviour, and compared allele-specific mRNA levels in post-mortem brain samples from suicide and non-suicide victims. 20726824 2011
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE Our findings suggest that the BDNF Val66Met polymorphism may contribute to methamphetamine dependence and psychosis in the Chinese population but not in other Malaysian ethnicities. 20736000 2010
Nonorganic psychosis
CUI: C0349204
Disease: Nonorganic psychosis
0.100 GeneticVariation BEFREE The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with risk for psychosis: evidence from a family-based association study. 16389585 2006