rs6265, BDNF;BDNF-AS

N. diseases: 272
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Body Weight
CUI: C0005910
Disease: Body Weight
0.800 GeneticVariation GWASCAT Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009
Body Weight
CUI: C0005910
Disease: Body Weight
0.800 GeneticVariation GWASDB Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
Waist-Hip Ratio
CUI: C0205682
Disease: Waist-Hip Ratio
0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
Smoking
CUI: C0037369
Disease: Smoking
0.700 GeneticVariation GWASCAT Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. 30643258 2019
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. 29273807 2018
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT Genome-wide association study identifies 112 new loci for body mass index in the Japanese population. 28892062 2017
Hip circumference
CUI: C0562350
Disease: Hip circumference
0.700 GeneticVariation GWASCAT New genetic loci link adipose and insulin biology to body fat distribution. 25673412 2015
Body mass index procedure
CUI: C0005893
Disease: Body mass index procedure
0.700 GeneticVariation GWASDB Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. 23001569 2013
Finding of body mass index
CUI: C0578022
Disease: Finding of body mass index
0.700 GeneticVariation GWASDB Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. 23001569 2013
Smoking Behaviors
CUI: C1519383
Disease: Smoking Behaviors
0.700 GeneticVariation GWASDB Genome-wide meta-analyses of smoking behaviors in African Americans. 22832964 2012
Finding of body mass index
CUI: C0578022
Disease: Finding of body mass index
0.700 GeneticVariation GWASDB Meta-analysis identifies common variants associated with body mass index in east Asians. 22344219 2012
Body mass index procedure
CUI: C0005893
Disease: Body mass index procedure
0.700 GeneticVariation GWASDB Meta-analysis identifies common variants associated with body mass index in east Asians. 22344219 2012
Smoking Behaviors
CUI: C1519383
Disease: Smoking Behaviors
0.700 GeneticVariation GWASDB Genome-wide meta-analyses identify multiple loci associated with smoking behavior. 20418890 2010
Smoking
CUI: C0037369
Disease: Smoking
0.700 GeneticVariation GWASCAT Genome-wide meta-analyses identify multiple loci associated with smoking behavior. 20418890 2010
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009
Body mass index procedure
CUI: C0005893
Disease: Body mass index procedure
0.700 GeneticVariation GWASDB Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009
Finding of body mass index
CUI: C0578022
Disease: Finding of body mass index
0.700 GeneticVariation GWASDB Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009
Mood Disorders
CUI: C0525045
Disease: Mood Disorders
0.100 GeneticVariation BEFREE Preliminary evidence suggests that BDNF (brain derived neurotrophic factor) rs6265 genetic polymorphism, BDNF gene promotor methylation and BDNF serum levels might play an important role in the pathogenesis of affective disorders. 30929061 2020
Depressive Symptoms
CUI: C0086132
Disease: Depressive Symptoms
0.100 GeneticVariation BEFREE Thus, we assessed whether the functional single nucleotide polymorphism (SNP) on the BDNF gene, Val66Met, moderated the relationship between depressive symptoms and perceived social support and unsupportive relationships, and whether these associations differed by gender. 31364951 2020
Depressive Symptoms
CUI: C0086132
Disease: Depressive Symptoms
0.100 GeneticVariation BEFREE BDNF (rs6265) and CRY1 (rs2287161) variants have been associated with more depressive symptoms in people with PD. 31292011 2020
Mental Depression
CUI: C0011570
Disease: Mental Depression
0.100 GeneticVariation BEFREE The association between BDNF Val66Met and SI was modeled using logistic regression adjusted for age and sex, and in secondary analyses also for depression. 30329132 2020