rs63751273, MAPT

N. diseases: 42
Disease: Memory impairment ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Memory impairment
CUI: C0233794
Disease: Memory impairment
0.030 GeneticVariation BEFREE Expression of P301L-hTau in mouse MEC induces hippocampus-dependent memory deficit. 28634382 2017
Memory impairment
CUI: C0233794
Disease: Memory impairment
0.030 GeneticVariation BEFREE The present study was undertaken to examine whether lycopene or lycopene/vitamin E could exert protective effects on memory deficit and oxidative stress in tau transgenic mice expressing P301L mutation. 28269786 2017
Memory impairment
CUI: C0233794
Disease: Memory impairment
0.030 GeneticVariation BEFREE Forebrain-specific over-expression of human tau(P301L), a mutation associated with frontotemporal dementia with parkinsonism linked to chromosome 17, in rTg4510 mice results in the formation of NFTs, learning and memory impairment and massive neuronal death. 22027994 2012