|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
BEFREE |
The haplotype tagged by rs35923643-G (or its proxy SNP rs735665-A) is also known as the top risk allele for chronic lymphocytic leukemia (CLL), and a main increasing allele for general IgM.
|
29547969 |
2018 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
|
24292274 |
2014 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
|
24292274 |
2014 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.
|
23770605 |
2013 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.
|
23770605 |
2013 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
GWASDB |
Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.
|
22700719 |
2012 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
GWASCAT |
Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.
|
22700719 |
2012 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
BEFREE |
Common single nucleotide polymorphisms (SNPs) at 2q13 (rs17483466), 2q37.1 (rs13397985), 2q37.3 (rs757978), 6p25.3 (rs872071), 8q24.21 (rs2456449), 11q24.1 (rs735665), 15q21.3 (rs7169431), 15q23 (rs7176508), 16q24.1 (rs305061), and 19q13.32 (rs11083846) have been shown to confer a modest but significant increase in CLL risk.
|
20855867 |
2010 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
BEFREE |
Combined data provided statistically significant support for an association between genotypes at rs13397985, rs872071, rs735665, rs7176508 and rs11083846 and CLL risk.
|
20553269 |
2010 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
GWASCAT |
We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).
|
18758461 |
2008 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
BEFREE |
We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).
|
18758461 |
2008 |
|
Chronic Lymphocytic Leukemia
|
|
0.840 |
GeneticVariation
|
GWASDB |
We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).
|
18758461 |
2008 |