Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.080 GeneticVariation BEFREE No variant for either rs75932628 or rs2234253 was found in both PD and control cohorts. 26704436 2016
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.080 GeneticVariation BEFREE Neither the entire PD nor the small PDD sample was associated with p.R47H. 26651418 2016
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.080 GeneticVariation BEFREE Our results corroborate and extend previous findings, concluding that the variant rs75932628-T (p.R47H) in TREM2 is not a risk factor for LA or PD in the Han Chinese population. 26758262 2016
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.080 GeneticVariation BEFREE We identified a significant association between rs75932628 and PD (P = 3.10E-03, odds ratio (OR) = 3.88, 95 % confidence interval (CI) 1.58-9.54) in No-Northern Europe subgroup, and significantly increased PD risks (P = 0.01 for Mann-Whitney test) in No-Northern Europe subgroup than in Northern Europe subgroup. 26365049 2016
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.080 GeneticVariation BEFREE Assessment of TREM2 rs75932628 association with Parkinson's disease and multiple system atrophy in a Chinese population. 26058955 2015
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.080 GeneticVariation BEFREE The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease. 25936935 2015
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.080 GeneticVariation BEFREE Rs75932628-T (p.R47H) was found in 0.2% of PD cases (1/476) but in none of the controls (0/432, p = 1.000), with a minor allele frequency of 0.06% among the 908 subjects. 24602511 2014
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.080 GeneticVariation BEFREE Our results suggest that the TREM2 p.R47H substitution is a risk factor for frontotemporal dementia and Parkinson's disease in addition to Alzheimer's disease. 23800361 2013