Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Mild cognitive disorder
CUI: C1270972
Disease: Mild cognitive disorder
0.020 GeneticVariation BEFREE Furthermore, we tested whether rs75932628 shows association with amyloid beta (Aβ42) and total-tau protein levels in the cerebrospinal fluid (CSF) of 828 individuals with AD or mild cognitive impairment. 25936935 2015
Mild cognitive disorder
CUI: C1270972
Disease: Mild cognitive disorder
0.020 GeneticVariation BEFREE Independent voxel-based morphometry analysis of the Spanish set as well as conjunction and joint analyses revealed substantial gray matter loss in orbitofrontal cortex and anterior cingulate cortex with relative preservation of parietal lobes in AD and/or mild cognitive impairment TREM2 p.R47H carriers, suggesting that TREM2 p.R47H variant is associated with certain clinical and neuroimaging AD features in addition to the increased TREM2 p.R47H atrophy in temporal lobes as described previously. 25027412 2014