Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome.
|
31822818 |
2019 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
The BDNF-Val66Met polymorphism may index susceptibility to expression of psychosis along a spectrum.
|
29785763 |
2019 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study suggests that the common Val66Met polymorphism of the BDNF gene may modulate the relationship between life stress and calorie intake in subjects at risk for psychosis.
|
27629407 |
2018 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
These findings provide evidence of the important role of early cannabis use and the Val66Met BDNF polymorphism on age at psychosis onset and they point out to sex-specific differences in cannabis use patterns.
|
28142064 |
2017 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
One of the most studied genetic phenotypes for psychosis is brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms.
|
26603624 |
2016 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Here we comprehensively review the role and relevance of the Val66Met polymorphism in psychiatric disorders, with emphasis on suicidal behavior and anxiety, eating, mood and psychotic disorders.
|
25824305 |
2015 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Further, our study supports a two hit model including a history of childhood trauma as well as genetic vulnerability (met carriers of the BDNF val66met) behind reduced volume of hippocampal subfields in psychosis.
|
25246365 |
2014 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
A complex interplay between BDNF serum concentrations, personality traits, BDNF Val66Met polymorphism, and psychotic symptomatology has been arisen but further investigation is needed to better clarify the observed associations.
|
23333821 |
2013 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
The present study aimed to explore possible effects of BDNF Val66Met polymorphism variations on progressive structural brain changes after 3 years from the first episode of psychosis.
|
23748016 |
2013 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses.
|
23876786 |
2013 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Results suggest the effects of the BDNF Val66Met allele may be different in patients with psychosis than in healthy adults.
|
22192502 |
2012 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
We performed BDNF val66met variant genotyping, cognitive testing (verbal fluency and digit spans) and assessments of symptom severity (as assessed with the PANSS) in a population-based sample of FEP patients (77 with schizophreniform psychosis and 53 with affective psychoses) and 191 neighboring healthy controls.
|
23429848 |
2012 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
The Met allele of the functional polymorphism, BDNF Val66Met, is associated with psychotic disorders.
|
21728904 |
2012 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
We performed a family-based association study and ETDT analyses of the Val66Met polymorphism in nuclear families with at least one subject affected by major psychosis with suicidal behaviour, and compared allele-specific mRNA levels in post-mortem brain samples from suicide and non-suicide victims.
|
20726824 |
2011 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results had adequate statistical power to suggest that BDNF Val66Met was not related to susceptibility to AD or the onset of AD, but that presence of one or two Met alleles of BDNF Val66Met polymorphism might present a risk factor for psychosis in AD.
|
21044653 |
2011 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our findings suggest that the BDNF Val66Met polymorphism may contribute to methamphetamine dependence and psychosis in the Chinese population but not in other Malaysian ethnicities.
|
20736000 |
2010 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Although there are some limitations on the study, our results indicate there is a lack of association between the Val66Met polymorphism and either of the two psychoses.
|
17417060 |
2007 |
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with risk for psychosis: evidence from a family-based association study.
|
16389585 |
2006 |