PENK, proenkephalin, 5179

N. diseases: 124; N. variants: 5
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0013386
Disease: Dyskinesia, Drug-Induced
Dyskinesia, Drug-Induced 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders Disease or Syndrome 32 0.500 None 1.000 2 1998 2010
CUI: C0030193
Disease: Pain
Pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 1554 196 0.380 None 1.000 9 1998 2017
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 156 23 0.330 None 1.000 3 2006 2012
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		disease Neoplasms; Male Urogenital Diseases Neoplastic Process 4502 1082 0.320 None 1.000 3 2005 2014
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 81 46 0.320 None 0.500 2 1999 2007
CUI: C0006870
Disease: Cannabis Dependence
Cannabis Dependence 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 40 13 0.320 None 1.000 2 2 2012 2015
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		group Nervous System Diseases Disease or Syndrome 977 39 0.310 None 1.000 2 1986 2001
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 577 441 0.310 None < 0.001 1 2007 2007
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 1719 297 0.300 None 0.750 4 2006 2014
CUI: C0011570
Disease: Mental Depression
Mental Depression 		disease Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 1478 271 0.300 None 0.750 4 2006 2014
CUI: C0751362
Disease: Narcolepsy-Cataplexy Syndrome
Narcolepsy-Cataplexy Syndrome 		disease Nervous System Diseases; Mental Disorders Disease or Syndrome 30 7 0.300 None 1.000 1 2007 2007
CUI: C0027412
Disease: Opioid-Related Disorders
Opioid-Related Disorders 		group Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 12 23 0.300 None 1.000 1 1999 1999
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		group Neoplasms; Male Urogenital Diseases Neoplastic Process 1722 31 0.300 None 1.000 1 2007 2007
CUI: C0524661
Disease: Narcotic Abuse
Narcotic Abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 6 0.300 None 1.000 1 1999 1999
CUI: C0751088
Disease: Dyskinesia, Medication-Induced
Dyskinesia, Medication-Induced 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Chemically-Induced Disorders Disease or Syndrome 15 0.300 None 1.000 1 1998 1998
CUI: C0458259
Disease: Pain, Crushing
Pain, Crushing 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 2005 2005
CUI: C0751407
Disease: Pain, Migratory
Pain, Migratory 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 2005 2005
CUI: C0029095
Disease: Opioid abuse
Opioid abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 16 0.300 None 1.000 1 1999 1999
CUI: C4551993
Disease: Amyotrophic Lateral Sclerosis, Familial
Amyotrophic Lateral Sclerosis, Familial 		disease Nutritional and Metabolic Diseases; Nervous System Diseases Disease or Syndrome 130 68 0.300 None 1.000 1 2002 2002
CUI: C0458257
Disease: Pain, Splitting
Pain, Splitting 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 2005 2005
CUI: C4551628
Disease: Opiate Abuse
Opiate Abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 12 0.300 None 1.000 1 1999 1999
CUI: C0234230
Disease: Pain, Burning
Pain, Burning 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 56 0.300 None 1.000 1 2005 2005
CUI: C0234254
Disease: Radiating pain
Radiating pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 51 0.300 None 1.000 1 2005 2005
CUI: C1862941
Disease: Amyotrophic Lateral Sclerosis, Sporadic
Amyotrophic Lateral Sclerosis, Sporadic 		disease Nutritional and Metabolic Diseases; Nervous System Diseases Disease or Syndrome 173 90 0.300 None 1.000 1 2002 2002
CUI: C0234238
Disease: Ache
Ache 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 2005 2005