Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.310 None 1.000 5 0 1979 2011
Entrez Id: 4986
Gene Symbol: OPRK1
OPRK1
P41145 opioid receptor kappa 1 G-protein coupled receptor 156 0.555 0.615 4.1E-05 0.320 None 1.000 4 0 1998 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.330 None 1.000 4 0 2003 2019
Entrez Id: 4852
Gene Symbol: NPY
NPY
P01303 neuropeptide Y Signaling 381 0.447 0.846 0.14 0.320 None 1.000 3 0 2001 2008
Entrez Id: 2353
Gene Symbol: FOS
FOS
P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 528 0.411 0.885 0.26 0.300 None 1.000 3 0 2004 2008
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
P31645 solute carrier family 6 member 4 Transporter 440 0.429 0.808 0.25 0.320 None 1.000 3 0 1997 2006
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6
P11509 cytochrome P450 family 2 subfamily A member 6 133 0.556 0.731 5.4E-09 0.030 None 1.000 3 0 2006 2019
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
P29274 adenosine A2a receptor G-protein coupled receptor 213 0.526 0.769 0.60 0.300 None 1.000 3 0 2004 2006
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.030 None 0.667 3 0 1999 2008
Entrez Id: 1385
Gene Symbol: CREB1
CREB1
P16220 cAMP responsive element binding protein 1 294 0.463 0.885 1.00 0.310 None 1.000 2 0 2009 2019
Entrez Id: 1392
Gene Symbol: CRH
CRH
P06850 corticotropin releasing hormone Signaling 402 0.439 0.808 0.72 0.300 None 1.000 2 0 2004 2009
Entrez Id: 1815
Gene Symbol: DRD4
DRD4
P21917 dopamine receptor D4 G-protein coupled receptor 189 0.517 0.577 9.3E-09 0.020 None 1.000 2 0 1997 2007
Entrez Id: 2890
Gene Symbol: GRIA1
GRIA1
P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 126 0.570 0.577 1.00 0.300 None 1.000 2 0 2001 2003
Entrez Id: 6754
Gene Symbol: SSTR4
SSTR4
P31391 somatostatin receptor 4 G-protein coupled receptor 273 0.469 0.846 3.7E-13 0.020 None 1.000 2 0 2014 2015
Entrez Id: 887
Gene Symbol: CCKBR
CCKBR
P32239 cholecystokinin B receptor G-protein coupled receptor 105 0.573 0.615 2.1E-06 0.300 None 1.000 2 0 1998 2002
Entrez Id: 8864
Gene Symbol: PER2
PER2
O15055 period circadian regulator 2 Transcription factor 238 0.488 0.846 0.71 0.300 None 1.000 2 0 2010 2010
Entrez Id: 57537
Gene Symbol: SORCS2
SORCS2
Q96PQ0 sortilin related VPS10 domain containing receptor 2 Transporter 19 0.743 0.346 3.2E-03 0.020 None 1.000 2 0 2018 2019
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
O00519 fatty acid amide hydrolase 177 0.545 0.692 4.4E-11 0.300 None 1.000 2 0 2008 2009
Entrez Id: 5187
Gene Symbol: PER1
PER1
O15534 period circadian regulator 1 Transcription factor 111 0.556 0.731 2.9E-04 0.300 None 1.000 1 0 2010 2010
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 2008 2008
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
Q13519 prepronociceptin Signaling 103 0.603 0.577 1.5E-02 0.300 None 1.000 1 0 2000 2000
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
P01563 interferon alpha 2 355 0.442 0.885 0.300 None 1.000 1 0 1988 1988
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.010 None 1.000 1 0 2012 2012
Entrez Id: 3574
Gene Symbol: IL7
IL7
P13232 interleukin 7 275 0.464 0.808 0.93 0.010 None 1.000 1 0 2017 2017