Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27102
Gene Symbol: EIF2AK1
EIF2AK1
0.300 Biomarker disease CTD_human Heme-regulated eIF2α kinase plays a crucial role in protecting erythroid cells against Pb-induced hemolytic stress. 25411909 2015
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1
0.300 Biomarker disease CTD_human Phenotypic spectrum of COL4A1 mutations: porencephaly to schizencephaly. 23225343 2013
Entrez Id: 3704
Gene Symbol: ITPA
ITPA
0.300 Therapeutic disease CTD_human Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction. 20547162 2010
Entrez Id: 2056
Gene Symbol: EPO
EPO
0.300 Therapeutic disease CTD_human Anemia--a complication of antiviral treatment in chronic viral hepatitis C. 20446436 2009
Entrez Id: 2056
Gene Symbol: EPO
EPO
0.300 Therapeutic disease CTD_human Definition and management of anemia in patients infected with hepatitis C virus. 16629641 2006
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human Autoimmune disorders during interferon therapy in a patient with chronic hepatitis C infection: how many of them can be observed in a single patient? 16633111 2006
Entrez Id: 6521
Gene Symbol: SLC4A1
SLC4A1
0.300 Biomarker disease CTD_human Monovalent cation leaks in human red cells caused by single amino-acid substitutions in the transport domain of the band 3 chloride-bicarbonate exchanger, AE1. 16227998 2005
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human Factors contributing to ribavirin dose reduction due to anemia during interferon alfa2b and ribavirin combination therapy for chronic hepatitis C. 15293138 2004
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Biomarker disease CTD_human Ribavirin: new preparation. An advance, but still no cure-all. 11010742 2000
Entrez Id: 2056
Gene Symbol: EPO
EPO
0.300 Therapeutic disease CTD_human Nifedipine and haemolytic anaemia. 10733367 2000
Entrez Id: 2729
Gene Symbol: GCLC
GCLC
0.300 Biomarker disease CTD_human The molecular basis of a case of gamma-glutamylcysteine synthetase deficiency. 10515893 1999
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
0.300 Biomarker disease CTD_human Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency. 9884342 1999
Entrez Id: 6710
Gene Symbol: SPTB
SPTB
0.300 Biomarker disease CTD_human Mutation of a highly conserved residue of betaI spectrin associated with fatal and near-fatal neonatal hemolytic anemia. 9005995 1997
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
0.300 Biomarker disease CTD_human Glyburide-induced acute haemolysis in a G6PD-deficient patient with NIDDM. 8562390 1996
Entrez Id: 2821
Gene Symbol: GPI
GPI
0.300 Biomarker disease CTD_human Molecular analysis of glucose phosphate isomerase deficiency associated with hereditary hemolytic anemia. 8822954 1996
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
0.300 Biomarker disease CTD_human Aspirin-induced acute haemolytic anaemia in glucose-6-phosphate dehydrogenase-deficient children with systemic arthritis. 2502894 1989
Entrez Id: 7167
Gene Symbol: TPI1
TPI1
0.300 Biomarker disease CTD_human Human triose-phosphate isomerase deficiency: a single amino acid substitution results in a thermolabile enzyme. 2876430 1986
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
0.300 Biomarker disease CTD_human [Acute kidney failure and hemolytic anemia caused by erythrocytic G6PD dificit revealed by chloroquine administration]. 4794122 1973
Entrez Id: 2936
Gene Symbol: GSR
GSR
0.300 Biomarker disease CTD_human [A new enzymopenic hemolytic anemia with glutathione reductase deficiency]. 13931269 1962
Entrez Id: 8526
Gene Symbol: DGKE
DGKE
0.100 CausalMutation disease CLINVAR
Entrez Id: 7706
Gene Symbol: TRIM25
TRIM25
0.100 CausalMutation disease CLINVAR
Entrez Id: 5277
Gene Symbol: PIGA
PIGA
0.030 GeneticVariation disease BEFREE Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia caused by the expansion of a hematopoietic progenitor cell that has acquired a mutation in the X-linked PIGA gene. 19074066 2008
Entrez Id: 5277
Gene Symbol: PIGA
PIGA
0.030 Biomarker disease BEFREE Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia that is characterized by a deficiency of glycosylphosphatidylinositol-anchored membrane proteins due to phosphatidylinositol glycan-class A (PIG-A) gene abnormalities in various lineages of peripheral blood cells and hematopoietic precursors. 11301179 2001
Entrez Id: 5277
Gene Symbol: PIGA
PIGA
0.030 GeneticVariation disease BEFREE Paroxysmal nocturnal hemoglobinuria is an acquired hemolytic anemia associated with somatic mutations in the X-linked gene PIG-A, which encodes a protein involved in the biosynthesis of glycosyl phosphatidylinositol anchors. 8541557 1995