Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
0.010 AlteredExpression disease LHGDN We show that elevated YKL-40 levels are not correlated with the severity of subarachnoid haemorrhage and cannot be used as a serological marker of inflammation in patients with an aneurysm rupture. 18280741 2008
Entrez Id: 3002
Gene Symbol: GZMB
GZMB
0.010 AlteredExpression disease LHGDN We performed immunohistochemistry for the cytotoxic proteins perforin and granzyme B on paraffin-embedded, formalin-fixed coronary artery aneurysm tissue from 6 children who died in the acute stage of KD. 15818305 2005
Entrez Id: 5551
Gene Symbol: PRF1
PRF1
0.010 AlteredExpression disease LHGDN CD8 T lymphocytes do not express cytotoxic proteins in coronary artery aneurysms in acute Kawasaki disease. 15818305 2005
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.010 AlteredExpression disease LHGDN Cytosol levels of cytokines [interleukins 1b, 6, 8 (IL-1b, 6, 8), tumor necrosis factor-alpha (TNF-alpha)] in aneurysm walls were evaluated in a prospective non-randomized study of 57 patients. 12850808 2002
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.010 AlteredExpression disease LHGDN More pronounced inflammatory changes and higher cytosol cytokine levels [IL6 (p<0.001), IL8 (p<0.0003) and TNFalpha (p<0.002)] were found in the walls of ruptured aneurysms than in the asymptomatic aneurysms. 12850808 2002
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
0.010 AlteredExpression disease LHGDN More pronounced inflammatory changes and higher cytosol cytokine levels [IL6 (p<0.001), IL8 (p<0.0003) and TNFalpha (p<0.002)] were found in the walls of ruptured aneurysms than in the asymptomatic aneurysms. 12850808 2002
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.020 AlteredExpression disease LHGDN The systemic expressions of MMP-2 and MMP-9 were strongly associated with vasculo-Behçet's disease, particularly aneurysmatic involvement, suggesting their pathogenetic roles in vasculo-Behçet's disease complicated with aneurysm formation. 17949555 2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.020 AlteredExpression disease LHGDN Matrix metalloproteinases 2 and 9 in human atherosclerotic and non-atherosclerotic cerebral aneurysms. 16987162 2006
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
0.100 CausalMutation disease CLINVAR
Entrez Id: 81031
Gene Symbol: SLC2A10
SLC2A10
0.100 CausalMutation disease CLINVAR
Entrez Id: 4763
Gene Symbol: NF1
NF1
0.100 CausalMutation disease CLINVAR
Entrez Id: 1289
Gene Symbol: COL5A1
COL5A1
0.100 GeneticVariation disease CLINVAR
Entrez Id: 4629
Gene Symbol: MYH11
MYH11
0.100 GeneticVariation disease CLINVAR
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.100 GeneticVariation disease CLINVAR
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
0.100 CausalMutation disease CLINVAR
Entrez Id: 4638
Gene Symbol: MYLK
MYLK
0.100 GeneticVariation disease CLINVAR
Entrez Id: 1290
Gene Symbol: COL5A2
COL5A2
0.100 GeneticVariation disease CLINVAR
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
0.100 GeneticVariation disease CLINVAR
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
0.100 GeneticVariation disease CLINVAR
Entrez Id: 10056
Gene Symbol: FARSB
FARSB
0.100 CausalMutation disease CLINVAR
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
0.100 GeneticVariation disease CLINVAR
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
0.110 GeneticVariation disease LHGDN This case suggested that the COL3A1 gene could be one of etiologically linked genes in isolated vasculopathies such as aortic dissected aneurysm or CAD, although being rare. 18389341 2008
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
0.110 GeneticVariation disease CLINVAR
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
0.110 CausalMutation disease CLINVAR
Entrez Id: 50507
Gene Symbol: NOX4
NOX4
0.200 Biomarker disease RGD Role of mineralocorticoid receptor on experimental cerebral aneurysms in rats. 19620512 2009