Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 GeneticVariation group BEFREE We investigated whether KIR genes and their ligands affect the occurrence of CMV infection in a group of 138 kidney transplant recipients who were observed for 720 days posttransplantation. 30696053 2019
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 Biomarker group BEFREE Multivariate analysis showed that donor-recipient KIR ligand graft-versus-host or host-versus-graft direction mismatch was associated with increased refractory CMV infection (Hazard ratio = 2·556, 95% confidence interval, 1·377-4·744, P = 0·003) post-transplantation. 28466469 2017
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 GeneticVariation group BEFREE Presence of KIR2DS2 was associated with a worsening of HSCT outcome while reactivation of cytomegalovirus (CMV) infection improved the outcome of patients with one or more KIR ligands missing. 27394130 2016
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 Biomarker group BEFREE In this study, we set out to determine whether a protective effect of KIR genes over CMV infection is seen in Mexican pregnant women. 27277336 2016
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 GeneticVariation group BEFREE There was no significant difference between the two genotype groups with regard to occurrence of CMV disease, although there was a trend toward a lower incidence of CMV disease in recipients carrying the KIR-AA genotype. 25427165 2015
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 AlteredExpression group BEFREE Since the respective activities of the different KIR proteins expressed by NK cells during CMV infection have not been extensively studied, we analyzed the expression of KIRs in a cohort of 22 CMV-IgG(+) renal transplant patients at the time of CMV reactivation, after antiviral therapy and 6 months later. 25158213 2014
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 Biomarker group BEFREE Analysis of a cohort of previously human cytomegalovirus (HCMV)-negative patients, who developed primary HCMV infection following HCMV-positive renal transplant (n=76), revealed an increase in the frequency of KIR genes located on the telomeric region of B haplotypes (Tel B). 25253288 2014
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 Biomarker group BEFREE Collaborative studies suggested that both activating and inhibitory KIR and functionally relevant MBL2 haplotypes are important factors for control of CMV infection in the elderly and therefore for chronic low-grade inflammation. 23302099 2013
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 Biomarker group BEFREE We studied a cohort of 339 kidney transplant recipients to elucidate which KIR genes protect from CMV infection. 21486386 2011
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 GeneticVariation group BEFREE The number of activating KIR genes inversely correlates with the rate of CMV infection/reactivation in kidney transplant recipients. 18444913 2008
Entrez Id: 3811
Gene Symbol: KIR3DL1
KIR3DL1
0.100 GeneticVariation group BEFREE We have shown that the absence of the HLA-C ligand for inhibitory KIR and the presence of activating KIR genes in the recipients were both associated with a lower rate of CMV infection after transplantation. 19032228 2008