Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.620 Biomarker disease PSYGENET GABAergic functions, expressed in extracellular paired-pulse depression, and in IPSCs recorded in dentate granular cells were enhanced in Tg-SOD-1 mice. 10594078 1999
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.620 Biomarker disease PSYGENET The changes in mitochondrial activity in brain and reduced expressions of superoxide dismutase (SOD1, SOD2), mitofusin (Mfn1, Mfn2) as well as brain-derived neurotrophic factor (BDNF) suggest that both CORT and CUMS may impair mitochondrial function and/or expressions of mitofusion and antioxidant enzymes that, in turn, may increase oxidative stress and reduce energy production in brain with depression-like behaviors. 22244747 2012
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.620 Biomarker disease HPO
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.620 Biomarker disease CTD_human Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment. 19605942 2009
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.620 GeneticVariation disease BEFREE If confirmed by further investigations, the observed association between depression and executive functions suggests the need for a careful screening and treatment of depression, to avoid overestimation of cognitive involvement and possibly improve cognitive performances in ALS. 29674987 2018
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.620 AlteredExpression disease BEFREE Several behavior tests (sucrose preference test (SPT), forced swimming test (FST) and tail suspension test (TST)) and biochemical parameters (IL-6, TNF-α and SOD levels) were used to evaluate the antidepressive effect of PF on LPS-induced depression model. 31052597 2019