Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.450 Biomarker group BEFREE Our aim was to investigate the role of epigenetics in Rac1 regulation in diabetes. 30347077 2018
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.450 Biomarker group BEFREE Our data suggest that the pharmacological inhibition of Rac1 could represent a novel therapeutic strategy to reduce endothelial dysfunction and platelet hyperaggregation in diabetes mellitus. 29626150 2018
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.450 Biomarker group BEFREE In this Commentary, we overviewed the emerging evidence implicating potential cross-talk between Rac1 and ceramide signaling pathways in the onset of metabolic dysregulation of the islet β-cell culminating in impaired physiological insulin secretion, loss of β-cell mass and the onset of diabetes. 29715450 2018
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.450 Biomarker group BEFREE The primary objective of the current study was to determine the role of Rac1 in CD36 activation and its impact on β-cell dysfunction in diabetes mellitus. 27912197 2017
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.450 Biomarker group BEFREE Paradoxically, emerging evidence in multiple cell types, including the islet β-cell, suggests key roles for Rac1 in the onset of cellular dysfunction under conditions of metabolic stress and diabetes. 28202288 2017
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.450 Biomarker group CTD_human Oxidative stress-mediated thrombospondin-2 upregulation impairs bone marrow-derived angiogenic cell function in diabetes mellitus. 23723366 2013
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
0.450 Biomarker group HPO