Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.110 GeneticVariation disease GWASDB A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. 22036096 2011
Entrez Id: 7145
Gene Symbol: TNS1
TNS1 		0.110 GeneticVariation disease BEFREE Single nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)). 24388013 2014
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.110 GeneticVariation disease BEFREE Homozygotes of the G-allele in IL-2 -330 T/G were at increased risk of hayfever (OR=2.6, 95%CI=1.3-5.2). 15005726 2004
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.110 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.110 GeneticVariation disease GWASCAT A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. 22036096 2011
Entrez Id: 7145
Gene Symbol: TNS1
TNS1 		0.110 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A 		0.100 GeneticVariation disease GWASCAT A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. 22036096 2011
Entrez Id: 286046
Gene Symbol: XKR6
XKR6 		0.100 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 10451
Gene Symbol: VAV3
VAV3 		0.100 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 7096
Gene Symbol: TLR1
TLR1 		0.100 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A 		0.100 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1 		0.100 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 773
Gene Symbol: CACNA1A
CACNA1A 		0.100 GeneticVariation disease CLINVAR
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3 		0.100 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 8809
Gene Symbol: IL18R1
IL18R1 		0.100 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 284110
Gene Symbol: GSDMA
GSDMA 		0.100 GeneticVariation disease GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013 2014
Entrez Id: 3596
Gene Symbol: IL13
IL13 		0.030 GeneticVariation disease BEFREE Of 60 tagging single-nucleotide polymorphisms covering eight genes (CSF2, IL3, IL4, IL13, CSF2RB, IL4R, IL13RA1, IL13RA2), several were related to pollen allergies among controls: IL4R rs3024647 (dominant OR: 1.5; 95% CI: 1.0-2.3; P = 0.04), CSF2RB rs16997517 (dominant OR: 2.2; 95% CI: 1.0-4.7; P = 0.04), and IL13 rs1800925 (per-allele OR: 1.7; 95% CI: 1.3-2.4; P = 0.0007). 21071541 2011
Entrez Id: 3567
Gene Symbol: IL5
IL5 		0.030 GeneticVariation disease BEFREE We cultured human nasal mucosa obtained from individuals with seasonal allergic rhinitis with either specific allergen, recombinant human IL-5 (rhIL-5), or allergen + soluble IL-5Ralpha (sIL-5Ralpha), shown to antagonize IL-5 function. 10640772 2000
Entrez Id: 3596
Gene Symbol: IL13
IL13 		0.030 GeneticVariation disease BEFREE Our data suggest lack of evidence for identifying the variant Arg110Glnat the IL13 locus as a genetic risk factor involved in the development of Japanese cedar pollinosis. 16272823 2006
Entrez Id: 90865
Gene Symbol: IL33
IL33 		0.030 GeneticVariation disease BEFREE IL-33-polymorphisms rs928413 and rs1342326 may account for an increased risk of hay fever with the age of 6 years. 27171815 2016
Entrez Id: 2312
Gene Symbol: FLG
FLG 		0.020 GeneticVariation disease BEFREE Our comprehensive screening suggested that population-specific FLG mutations may be a significant predisposing factor for hay fever (odds ratio = 2.01 [95% CI: 1.027-3.936, P < 0.05]), although the sample sizes of this study were too small for reliable subphenotype analysis on the association between FLG mutations and hay fever in the eczema patients and the noneczema individuals, and it is not clear whether the association between FLG mutations and hay fever is due to the close association between FLG mutations and hay fever patients with eczema. 24467288 2014
Entrez Id: 8288
Gene Symbol: EPX
EPX 		0.020 GeneticVariation disease LHGDN Our results might indicate that polymorphisms of the EPO gene are associated with Japanese cedar pollinosis. 15316147 2004
Entrez Id: 3566
Gene Symbol: IL4R
IL4R 		0.020 GeneticVariation disease BEFREE The differences in the involvements of loci of promoter region and Ile50Val in interleukin-4 receptor α chain gene between atopic dermatitis and Japanese cedar pollinosis. 21918367 2012
Entrez Id: 8288
Gene Symbol: EPX
EPX 		0.020 GeneticVariation disease BEFREE These results suggest that Pro358Leu in EPO is strongly involved in the development of cedar pollinosis. 14657871 2003
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.020 GeneticVariation disease BEFREE We found decreased OR for hayfever (OR=0.60, 95%CI=0.4-0.9) and sensitization to inhalant antigens (OR=0.5, 95%CI=0.4-0.8) in heterozygotes of the IL-6 -174 G/C polymorphism. 15005726 2004