Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 773
Gene Symbol: CACNA1A
CACNA1A
0.100 GeneticVariation disease CLINVAR
Entrez Id: 7593
Gene Symbol: MZF1
MZF1
0.010 GeneticVariation disease BEFREE Self-reported histories of hay fever and asthma were obtained from 3,808 pairs of adult twins 18 years and over registered with the Australian National Health Medical Research Council Twin Registry (1232 MZF, 567 MZM, 751 DZF, 352 DZM, 906 DZO). 2227373 1990
Entrez Id: 26136
Gene Symbol: TES
TES
0.010 Biomarker disease BEFREE Mouse mAb TES-C21(C21) recognizes an epitope on human IgE and, therefore, has potential as a therapeutic agent in patients with IgE-mediated allergies such as hay fever, food and drug allergies and extrinsic asthma. 8309946 1993
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
0.010 GeneticVariation disease BEFREE An important locus for Atopy (familial asthma, hay fever and eczema) has been localized to the 11q12-q13 region with the minimum recombination fraction around the CD20 gene. 7521709 1994
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.010 GeneticVariation disease BEFREE An important locus for Atopy (familial asthma, hay fever and eczema) has been localized to the 11q12-q13 region with the minimum recombination fraction around the CD20 gene. 7521709 1994
Entrez Id: 2996
Gene Symbol: GYPE
GYPE
0.010 Biomarker disease BEFREE Associations between blood groups and RAD (atopic bronchial asthma [ABA] and pollinosis), the severity of the disease and the type of sensitization were established, involving the ABO, MNSs and Duffy systems. 7551203 1995
Entrez Id: 28
Gene Symbol: ABO
ABO
0.010 GeneticVariation disease BEFREE Associations between blood groups and RAD (atopic bronchial asthma [ABA] and pollinosis), the severity of the disease and the type of sensitization were established, involving the ABO, MNSs and Duffy systems. 7551203 1995
Entrez Id: 27239
Gene Symbol: GPR162
GPR162
0.010 Biomarker disease BEFREE Resistance to RAD was associated with phenotypes A(II), AB(IV), N, Fya(+) and B(III)N. Markers for ABA and pollinosis were also revealed. 7551203 1995
Entrez Id: 2994
Gene Symbol: GYPB
GYPB
0.010 Biomarker disease BEFREE Associations between blood groups and RAD (atopic bronchial asthma [ABA] and pollinosis), the severity of the disease and the type of sensitization were established, involving the ABO, MNSs and Duffy systems. 7551203 1995
Entrez Id: 2993
Gene Symbol: GYPA
GYPA
0.010 Biomarker disease BEFREE Associations between blood groups and RAD (atopic bronchial asthma [ABA] and pollinosis), the severity of the disease and the type of sensitization were established, involving the ABO, MNSs and Duffy systems. 7551203 1995
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
0.010 Biomarker disease BEFREE Associations between blood groups and RAD (atopic bronchial asthma [ABA] and pollinosis), the severity of the disease and the type of sensitization were established, involving the ABO, MNSs and Duffy systems. 7551203 1995
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.020 AlteredExpression disease BEFREE Eotaxin mRNA and protein expression in chronic sinusitis and allergen-induced nasal responses in seasonal allergic rhinitis. 9409555 1997
Entrez Id: 3567
Gene Symbol: IL5
IL5
0.030 AlteredExpression disease BEFREE Nasal eosinophilia and IL-5 mRNA expression in seasonal allergic rhinitis induced by natural allergen exposure: effect of topical corticosteroids. 9802369 1998
Entrez Id: 3596
Gene Symbol: IL13
IL13
0.030 Biomarker disease BEFREE Here, we examine the intensity of polyclonally and Ag-stimulated IL-13 production by PBMC of 20 subjects with seasonal allergic rhinitis and 20 healthy controls. 9862737 1998
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
0.010 Biomarker disease BEFREE Our results indicate restricted TCR-V beta gene usage in cat and birch pollen allergies; we suggest that both genetic and environmental factors contribute to TCR-V beta gene expression and to the development of a specific T cell response. 9916751 1999
Entrez Id: 3567
Gene Symbol: IL5
IL5
0.030 AlteredExpression disease BEFREE Allergen induced mRNA expression of interleukin-5, but not of interleukin-4 and interferon-gamma, in peripheral blood mononuclear cells obtained before the pollen season predicts the clinical efficacy of immunotherapy for seasonal allergic rhinitis. 10652165 2000
Entrez Id: 3567
Gene Symbol: IL5
IL5
0.030 GeneticVariation disease BEFREE We cultured human nasal mucosa obtained from individuals with seasonal allergic rhinitis with either specific allergen, recombinant human IL-5 (rhIL-5), or allergen + soluble IL-5Ralpha (sIL-5Ralpha), shown to antagonize IL-5 function. 10640772 2000
Entrez Id: 3565
Gene Symbol: IL4
IL4
0.020 Biomarker disease BEFREE Allergen induced mRNA expression of interleukin-5, but not of interleukin-4 and interferon-gamma, in peripheral blood mononuclear cells obtained before the pollen season predicts the clinical efficacy of immunotherapy for seasonal allergic rhinitis. 10652165 2000
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.020 Biomarker disease BEFREE Allergen induced mRNA expression of interleukin-5, but not of interleukin-4 and interferon-gamma, in peripheral blood mononuclear cells obtained before the pollen season predicts the clinical efficacy of immunotherapy for seasonal allergic rhinitis. 10652165 2000
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.020 GeneticVariation disease BEFREE Among the correlations with the clinical parameters, we observed an increased risk of allergies (odds ratio, OR= 4.1; confidence interval, CI: 1.6-10.4), particularly hay fever (OR=5.6, CI: 1.8-17.1) in individuals homozygous for IFNG 13 CA-repeats. 11354638 2001
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.010 GeneticVariation disease BEFREE In combination with the TNF wildtype, the risk for hay fever increased to OR=8.4 (CI: 2.7-25.6). 11354638 2001
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.010 Biomarker disease BEFREE In summary, oligonucleotide microarray analysis of nasal biopsies and protein analyses of nasal fluids indicate that VEGF-A may be an important mediator in SAR. 12633568 2002
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
0.020 Biomarker disease BEFREE After diagnosing 351 subjects on the basis of an intradermal test, nasal provocation test, and questionnaire regarding nasal and conjunctival symptoms, we determined the blood-specific IgE values and genotypes of eosinophil peroxidase (EPO) and interleukin-4 receptor alpha-chain (IL4RA) in 145 patients with pollinosis and 206 healthy subjects, including 75 healthy subjects with higher specific IgE values. 14657871 2003
Entrez Id: 8288
Gene Symbol: EPX
EPX
0.020 GeneticVariation disease BEFREE These results suggest that Pro358Leu in EPO is strongly involved in the development of cedar pollinosis. 14657871 2003
Entrez Id: 3565
Gene Symbol: IL4
IL4
0.020 Biomarker disease BEFREE High contribution contrast between the genes of eosinophil peroxidase and IL-4 receptor alpha-chain in Japanese cedar pollinosis. 14657871 2003