Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 773
Gene Symbol: CACNA1A
CACNA1A
0.100 GeneticVariation disease CLINVAR
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.010 AlteredExpression disease LHGDN Epidermal growth factor receptor - but not histamine receptor - is upregulated in seasonal allergic rhinitis. 12757445 2003
Entrez Id: 7534
Gene Symbol: YWHAZ
YWHAZ
0.010 AlteredExpression disease BEFREE Phospholipase A2 mRNA expression in the nasal mucosa of healthy subjects and patients with seasonal allergic rhinitis. 15224635 2004
Entrez Id: 151056
Gene Symbol: PLB1
PLB1
0.010 AlteredExpression disease BEFREE Phospholipase A2 mRNA expression in the nasal mucosa of healthy subjects and patients with seasonal allergic rhinitis. 15224635 2004
Entrez Id: 2312
Gene Symbol: FLG
FLG
0.020 GeneticVariation disease BEFREE Filaggrin gene (FLG) mutations contribute to the development of eczema and asthma, but their contribution to sensitization and hay fever remains unclear. 19839980 2009
Entrez Id: 1439
Gene Symbol: CSF2RB
CSF2RB
0.010 GeneticVariation disease BEFREE CSF2RB rs16997517 was directly related to pollen allergies in controls and to reduced SCC risk. 21071541 2011
Entrez Id: 90865
Gene Symbol: IL33
IL33
0.030 GeneticVariation disease BEFREE IL-33-polymorphisms rs928413 and rs1342326 may account for an increased risk of hay fever with the age of 6 years. 27171815 2016
Entrez Id: 80315
Gene Symbol: CPEB4
CPEB4
0.010 Biomarker disease BEFREE CPEB4 and CREB might be implicated in the pathogenesis of SAR. 30616374 2019
Entrez Id: 6356
Gene Symbol: CCL11
CCL11
0.020 AlteredExpression disease BEFREE Eotaxin mRNA and protein expression in chronic sinusitis and allergen-induced nasal responses in seasonal allergic rhinitis. 9409555 1997
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.110 GeneticVariation disease GWASDB A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. 22036096 2011
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.110 GeneticVariation disease GWASCAT A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. 22036096 2011
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
0.100 GeneticVariation disease GWASCAT A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. 22036096 2011
Entrez Id: 2615
Gene Symbol: LRRC32
LRRC32
0.010 GeneticVariation disease BEFREE A variant near LRRC32 was a stronger risk factor for hay fever than for asthma, whereas the reverse was observed for variants in/near GSDMA and TSLP. 24388013 2014
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.020 GeneticVariation disease BEFREE After controlling for age group and sex using logistic regression, the odds of having hay fever were reduced by 88% (P = .009) in the TLR4 polymorphic group compared with the wild-type group. 18517079 2008
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
0.020 Biomarker disease BEFREE After diagnosing 351 subjects on the basis of an intradermal test, nasal provocation test, and questionnaire regarding nasal and conjunctival symptoms, we determined the blood-specific IgE values and genotypes of eosinophil peroxidase (EPO) and interleukin-4 receptor alpha-chain (IL4RA) in 145 patients with pollinosis and 206 healthy subjects, including 75 healthy subjects with higher specific IgE values. 14657871 2003
Entrez Id: 3567
Gene Symbol: IL5
IL5
0.030 AlteredExpression disease BEFREE Allergen induced mRNA expression of interleukin-5, but not of interleukin-4 and interferon-gamma, in peripheral blood mononuclear cells obtained before the pollen season predicts the clinical efficacy of immunotherapy for seasonal allergic rhinitis. 10652165 2000
Entrez Id: 3565
Gene Symbol: IL4
IL4
0.020 Biomarker disease BEFREE Allergen induced mRNA expression of interleukin-5, but not of interleukin-4 and interferon-gamma, in peripheral blood mononuclear cells obtained before the pollen season predicts the clinical efficacy of immunotherapy for seasonal allergic rhinitis. 10652165 2000
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.020 Biomarker disease BEFREE Allergen induced mRNA expression of interleukin-5, but not of interleukin-4 and interferon-gamma, in peripheral blood mononuclear cells obtained before the pollen season predicts the clinical efficacy of immunotherapy for seasonal allergic rhinitis. 10652165 2000
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.020 GeneticVariation disease BEFREE Among the correlations with the clinical parameters, we observed an increased risk of allergies (odds ratio, OR= 4.1; confidence interval, CI: 1.6-10.4), particularly hay fever (OR=5.6, CI: 1.8-17.1) in individuals homozygous for IFNG 13 CA-repeats. 11354638 2001
Entrez Id: 23765
Gene Symbol: IL17RA
IL17RA
0.010 AlteredExpression disease BEFREE Among these 3 genes, the expression of interleukin 17 receptor beta (IL17RB) was confirmed to be upregulated in SAR patients compared to that of the IL17RB gene in healthy, non-allergic controls. 21252617 2011
Entrez Id: 55540
Gene Symbol: IL17RB
IL17RB
0.020 AlteredExpression disease BEFREE Among these 3 genes, the expression of interleukin 17 receptor beta (IL17RB) was confirmed to be upregulated in SAR patients compared to that of the IL17RB gene in healthy, non-allergic controls. 21252617 2011
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
0.010 GeneticVariation disease BEFREE An important locus for Atopy (familial asthma, hay fever and eczema) has been localized to the 11q12-q13 region with the minimum recombination fraction around the CD20 gene. 7521709 1994
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
0.010 GeneticVariation disease BEFREE An important locus for Atopy (familial asthma, hay fever and eczema) has been localized to the 11q12-q13 region with the minimum recombination fraction around the CD20 gene. 7521709 1994
Entrez Id: 6351
Gene Symbol: CCL4
CCL4
0.010 AlteredExpression disease BEFREE Analysis of nasal fluid CCL4 protein confirmed lower levels in women with seasonal allergic rhinitis, before and during the pollen season. 18440239 2008
Entrez Id: 28
Gene Symbol: ABO
ABO
0.010 GeneticVariation disease BEFREE Associations between blood groups and RAD (atopic bronchial asthma [ABA] and pollinosis), the severity of the disease and the type of sensitization were established, involving the ABO, MNSs and Duffy systems. 7551203 1995