Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
0.010 GeneticVariation disease BEFREE The haplotype-based haplotype relative risk approach revealed that SNPs in SDA1 domain containing 1; chemokine, CXC motif, ligand (CXCL)-9; CXCL10; and CXCL11 were associated with SAR (P = .001-.04). 15753903 2005
Entrez Id: 4283
Gene Symbol: CXCL9
CXCL9
0.010 Biomarker disease BEFREE The haplotype-based haplotype relative risk approach revealed that SNPs in SDA1 domain containing 1; chemokine, CXC motif, ligand (CXCL)-9; CXCL10; and CXCL11 were associated with SAR (P = .001-.04). 15753903 2005
Entrez Id: 55153
Gene Symbol: SDAD1
SDAD1
0.010 Biomarker disease BEFREE The haplotype-based haplotype relative risk approach revealed that SNPs in SDA1 domain containing 1; chemokine, CXC motif, ligand (CXCL)-9; CXCL10; and CXCL11 were associated with SAR (P = .001-.04). 15753903 2005
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
0.020 GeneticVariation disease BEFREE The differences in the involvements of loci of promoter region and Ile50Val in interleukin-4 receptor α chain gene between atopic dermatitis and Japanese cedar pollinosis. 21918367 2012
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.020 AlteredExpression disease BEFREE The aim of this study was to clarify whether there are more regulatory T (Treg) and regulatory B (Breg) cells, and higher levels of IL-10-related transcription factors in subcutaneous immunotherapy (SCIT)-treated pollinosis patients than in non-SCIT-treated patients. 30860439 2019
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
0.020 Biomarker disease BEFREE The abundant presence and distribution of gene and protein expression of PAR 2 in different cell types in the nasal mucosa under normal situation, the increased expression of PAR 2 in epithelial cells and the increased number of eosinophils with PAR 2 suggest that PAR 2 may contribute to the pathogenesis of allergic diseases such as SAR. 16911360 2006
Entrez Id: 55065
Gene Symbol: SLC52A1
SLC52A1
0.010 Biomarker disease BEFREE The abundant presence and distribution of gene and protein expression of PAR 2 in different cell types in the nasal mucosa under normal situation, the increased expression of PAR 2 in epithelial cells and the increased number of eosinophils with PAR 2 suggest that PAR 2 may contribute to the pathogenesis of allergic diseases such as SAR. 16911360 2006
Entrez Id: 2150
Gene Symbol: F2RL1
F2RL1
0.010 Biomarker disease BEFREE The abundant presence and distribution of gene and protein expression of PAR 2 in different cell types in the nasal mucosa under normal situation, the increased expression of PAR 2 in epithelial cells and the increased number of eosinophils with PAR 2 suggest that PAR 2 may contribute to the pathogenesis of allergic diseases such as SAR. 16911360 2006
Entrez Id: 28955
Gene Symbol: DEXI
DEXI
0.010 GeneticVariation disease BEFREE The rs62026376:C allele associated with increased asthma with hay fever risk has been found to be associated also with decreased expression of the nearby DEXI gene in monocytes. 24388013 2014
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
0.010 GeneticVariation disease BEFREE The rs1229984 (ADH1B) was genotyped; alcohol consumption, hay fever and asthma were self-reported. 30209858 2019
Entrez Id: 64806
Gene Symbol: IL25
IL25
0.010 Biomarker disease BEFREE The IL-25 concentration in nasal secretions was significantly higher in patients with Japanese cedar pollinosis than in HCs. 29402661 2018
Entrez Id: 56005
Gene Symbol: MYDGF
MYDGF
0.010 Biomarker disease BEFREE The IL-25 concentration in nasal secretions was significantly higher in patients with Japanese cedar pollinosis than in HCs. 29402661 2018
Entrez Id: 3269
Gene Symbol: HRH1
HRH1
0.030 AlteredExpression disease BEFREE The H1R gene is upregulated in patients with pollinosis, and its expression level is correlated with the severity of nasal symptoms. 26980430 2016
Entrez Id: 90865
Gene Symbol: IL33
IL33
0.030 Biomarker disease BEFREE The IL-33-induced production of pro-inflammatory cytokines is a critical event that aggravates atopic diseases such as asthma, atopic dermatitis, and pollenosis and suggests that IL-33-blocking agents could represent new therapeutic drugs. 25213717 2014
Entrez Id: 80332
Gene Symbol: ADAM33
ADAM33
0.020 GeneticVariation disease BEFREE The ADAM33 gene has been identified as a potentially important asthma candidate gene and polymorphisms in this gene have been shown to be associated with asthma and seasonal allergic rhinitis. 24751681 2014
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
0.010 GeneticVariation disease BEFREE Statistically significant associations between the 3'ter MUC5AC simple nucleotide polymorphism (SNP) rs1132440 and various non-independent respiratory outcomes (bronchitis, wheeze, asthma, hay fever) were reported while the adjacent loci show slight (but largely non-statistically significant) differences, presumably reflective of linkage disequilibrium (allelic association) across the region. 23551418 2013
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
0.010 AlteredExpression disease LHGDN Soluble HLA-G and HLA-A,-B,-C serum levels in patients with allergic rhinitis. 18782112 2008
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
0.010 AlteredExpression disease LHGDN Soluble HLA-G and HLA-A,-B,-C serum levels in patients with allergic rhinitis. 18782112 2008
Entrez Id: 3135
Gene Symbol: HLA-G
HLA-G
0.010 AlteredExpression disease LHGDN Soluble HLA-G and HLA-A,-B,-C serum levels in patients with allergic rhinitis. 18782112 2008
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
0.010 AlteredExpression disease LHGDN Soluble HLA-G and HLA-A,-B,-C serum levels in patients with allergic rhinitis. 18782112 2008
Entrez Id: 7145
Gene Symbol: TNS1
TNS1
0.110 GeneticVariation disease BEFREE Single nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)). 24388013 2014
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.010 GeneticVariation disease BEFREE Single nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)). 24388013 2014
Entrez Id: 1052
Gene Symbol: CEBPD
CEBPD
0.010 Biomarker disease BEFREE Several genes related to immunity and regulation of transcription, such as FOS, JUN, and CEBPD, may play crucial roles during the process of SAR through the interactions with each other. 27435592 2017
Entrez Id: 3725
Gene Symbol: JUN
JUN
0.020 Biomarker disease BEFREE Several genes related to immunity and regulation of transcription, such as FOS, JUN, and CEBPD, may play crucial roles during the process of SAR through the interactions with each other. 27435592 2017
Entrez Id: 7593
Gene Symbol: MZF1
MZF1
0.010 GeneticVariation disease BEFREE Self-reported histories of hay fever and asthma were obtained from 3,808 pairs of adult twins 18 years and over registered with the Australian National Health Medical Research Council Twin Registry (1232 MZF, 567 MZM, 751 DZF, 352 DZM, 906 DZO). 2227373 1990