Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5
0.430 AlteredExpression disease BEFREE The expression of KCC2 protein was elevated by the treatment of GCK after SE, while the expression of NKCC1 protein was reversely down-regulated. 30254585 2018
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5
0.430 Biomarker disease BEFREE Tyrosine phosphorylation of KCC2 is thus likely to play a key role in regulating the degradation of KCC2, a process that may be responsible for pathological losses of KCC2 function that are evident in SE and other forms of epilepsy. 20600929 2010
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5
0.430 Biomarker disease BEFREE <i>Kcc2<sup>E/E</sup></i> mice also displayed disrupted lumbar spinal neuron locomotor rhythmogenesis and touch-evoked status epilepticus associated with markedly impaired KCC2-dependent Cl<sup>-</sup> extrusion. 31615901 2019
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5
0.430 Biomarker disease CTD_human Tyrosine phosphorylation of KCC2 is thus likely to play a key role in regulating the degradation of KCC2, a process that may be responsible for pathological losses of KCC2 function that are evident in SE and other forms of epilepsy. 20600929 2010
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5
0.430 Biomarker disease HPO