Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 GeneticVariation phenotype BEFREE Rats receiving adenovirus carrying the β-EP gene had significantly less severe withdrawal symptoms upon naloxone challenge. 21983207 2011
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Therapeutic phenotype CTD_human Circadian alteration in neurobiology during protracted opiate withdrawal in rats. 20738730 2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Biomarker phenotype CTD_human Circadian alteration in neurobiology during protracted opiate withdrawal in rats. 20738730 2010
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Biomarker phenotype CTD_human Nicotine-induced antinociception, rewarding effects, and physical dependence are decreased in mice lacking the preproenkephalin gene. 15689546 2005
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Biomarker phenotype CTD_human Withdrawal symptom intensities demonstrated an inverse correlation with beta-endorphin and met-enkephalin levels, a direct linear correlation with amplitude height of the evoked potential, and blood pressure and heart rate changes. 15714323 2005
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Therapeutic phenotype CTD_human Withdrawal symptom intensities demonstrated an inverse correlation with beta-endorphin and met-enkephalin levels, a direct linear correlation with amplitude height of the evoked potential, and blood pressure and heart rate changes. 15714323 2005
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Therapeutic phenotype CTD_human Nicotine-induced antinociception, rewarding effects, and physical dependence are decreased in mice lacking the preproenkephalin gene. 15689546 2005
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Biomarker phenotype CTD_human In view of the appearance of mild withdrawal signs during this method of treatment, the observed increases in ACTH and cortisol levels probably reflect the inability of AES to suppress withdrawal symptoms induced by naloxone completely. 225122 1979
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Therapeutic phenotype CTD_human In view of the appearance of mild withdrawal signs during this method of treatment, the observed increases in ACTH and cortisol levels probably reflect the inability of AES to suppress withdrawal symptoms induced by naloxone completely. 225122 1979