Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
0.010 Biomarker phenotype BEFREE Combined CEA and cholesterol determinations increased the sensitivity for diagnosing carcinomatosis from 70% with cytology alone to 84% and established the correct diagnosis in 16 of 31 carcinomatosis cases with inconclusive cytology. 31028099 2019
Entrez Id: 3135
Gene Symbol: HLA-G
HLA-G
0.010 AlteredExpression phenotype BEFREE High Expression of HLA-G in Ovarian Carcinomatosis: The Role of Interleukin-1β. 30802770 2019
Entrez Id: 410
Gene Symbol: ARSA
ARSA
0.010 Biomarker phenotype BEFREE Compared to Group 1, those who underwent PDS during the latter 2 time periods had higher ASA scores (p < 0.001), higher-stage disease (p < 0.001), and more often had carcinomatosis (p = 0.015) and bulky UAD (p = 0.009). 30126704 2018
Entrez Id: 972
Gene Symbol: CD74
CD74
0.010 Biomarker phenotype BEFREE MIF/CD74 axis is a target for novel therapies in colon carcinomatosis. 28114961 2017
Entrez Id: 29991
Gene Symbol: OBP2A
OBP2A
0.010 Biomarker phenotype BEFREE Furthermore, OBP-301 significantly reduced the size of tumors (P < 0.01) and ascites even in a late-stage carcinomatosis peritonitis model. 27171483 2017
Entrez Id: 3835
Gene Symbol: KIF22
KIF22
0.010 Biomarker phenotype BEFREE Furthermore, OBP-301 significantly reduced the size of tumors (P < 0.01) and ascites even in a late-stage carcinomatosis peritonitis model. 27171483 2017
Entrez Id: 6591
Gene Symbol: SNAI2
SNAI2
0.010 Biomarker phenotype BEFREE In early stages, poorly cohesive carcinomas can display 3 histogenetic pathways, with particular molecular behaviors: "carcinoma with intraepithelial pagetoid onset" (with or without a switch from E-cadherin to SLUG positivity), "carcinoma with early lymphatic invasion" (carcinoma limited to mucosa but with carcinomatosis of the lymph vessels from subjacent layers), and "microglandular-type poorly cohesive carcinoma" (the onset is similar with adenocarcinoma but abrupt dedifferentiation can be seen in the submucosa, with persistence of a dual component in the deep layers). 26496316 2015
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.010 Biomarker phenotype BEFREE Cell membrane β-catenin was significantly increased in both DPAM and PMCA patients receiving antibiotics. 23743566 2013
Entrez Id: 3561
Gene Symbol: IL2RG
IL2RG
0.010 Biomarker phenotype BEFREE The human ovarian carcinoma SK-OV-3 cells implanted intraperitoneally (i.p.) in immunodeficient Rag2⁻/⁻;Il2rg⁻/⁻ mice gave rise to a progressive peritoneal carcinomatosis which mimics the fatal condition in advanced human patients.I.p. administration of R-LM249 strongly inhibited carcinomatosis, resulting in 60% of mice free from peritoneal diffusion, and 95% reduction in the total weight of neoplastic nodules. 23382683 2013
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
0.010 AlteredExpression phenotype BEFREE Moreover, a SKOV3 intraperitoneal ovarian carcinomatosis model was established to investigate the antitumor activity of HPEI+pVITRO-IP-10 complexes in nude mice. 22684947 2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.010 Biomarker phenotype BEFREE We then investigated the role of VEGFs and VEGF-R genotyping in determining either peritoneal carcinosis or hematogenous metastases in radically resected gastric cancer patients. 22808003 2012
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
0.010 Biomarker phenotype BEFREE Furthermore, CCL5 neutralization rendered the tumors more sensitive to a PDGFRβ-directed strategy in mice, this combination regimen offering the greatest protection against liver metastases and suppressing macroscopic peritoneal carcinosis. 22205974 2011
Entrez Id: 11259
Gene Symbol: FILIP1L
FILIP1L
0.010 AlteredExpression phenotype BEFREE Moreover, a SKOV3 intraperitoneal ovarian carcinomatosis model was established to investigate the antitumor activity of HPEI+FILIP1LΔC103-p complexes in nude mice. 21513424 2011
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
0.010 Biomarker phenotype BEFREE Furthermore, CCL5 neutralization rendered the tumors more sensitive to a PDGFRβ-directed strategy in mice, this combination regimen offering the greatest protection against liver metastases and suppressing macroscopic peritoneal carcinosis. 22205974 2011
Entrez Id: 3675
Gene Symbol: ITGA3
ITGA3
0.010 GeneticVariation phenotype BEFREE Tumor histology represents a crucial issue conditioning tumoral behavior; genotyping of rs2269772 (ITGA3) and rs11902171 (ITGV) may be a further asset in the definition of high-risk patients for peritoneal carcinosis among those relapsing after curative resection. 20926544 2011
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
0.010 AlteredExpression phenotype BEFREE Pseudomyxoma peritonei: is disease progression related to microbial agents? A study of bacteria, MUC2 AND MUC5AC expression in disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis. 18299935 2008
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.010 AlteredExpression phenotype BEFREE Pseudomyxoma peritonei: is disease progression related to microbial agents? A study of bacteria, MUC2 AND MUC5AC expression in disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis. 18299935 2008
Entrez Id: 302
Gene Symbol: ANXA2
ANXA2
0.010 Biomarker phenotype BEFREE These findings suggest that annexin 2 mediated fibrinolysis on the transitional cell carcinoma cells may play a role in inducing hemorrhagic disorder in vascular intimal carcinomatosis. 16524621 2007
Entrez Id: 5607
Gene Symbol: MAP2K5
MAP2K5
0.010 AlteredExpression phenotype BEFREE MEK5 may be one of the Stat3-regulated genes and plays its essential roles in oncogenesis mediated by aberrantly activated Stat3 signaling in breast carcinomatosis and malignancies. 15378007 2004
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
0.020 Biomarker phenotype BEFREE We have recently identified that the role of secreted protein acidic and rich in cysteine (SPARC) in amelioration of peritoneal ovarian carcinomatosis is mediated, at least in part, through mesothelial cell/lysophosphatidic acid-induced inflammatory response in ovarian cancer cells. 18813349 2008
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
0.020 Biomarker phenotype BEFREE Taken together, our findings underscore the use of SPARC as a potential therapeutic candidate in peritoneal ovarian carcinomatosis. 17325741 2007
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
0.030 Biomarker phenotype BEFREE The objective of this single institution retrospective study was to evaluate the survival impact of a multimodal opioid-sparing nonvolatile anesthetic technique (MA) in a group of patients who had undergone cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) for appendiceal carcinomatosis. 30829082 2019
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
0.030 Biomarker phenotype BEFREE Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is a treatment option in patients with carcinomatosis from high-grade appendiceal (HGA) primaries. 29288288 2018
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
0.030 Biomarker phenotype BEFREE A retrospective study of adults who had undergone CRS-HIPEC for appendiceal carcinomatosis was conducted. 28850197 2017
Entrez Id: 93974
Gene Symbol: ATP5IF1
ATP5IF1
0.200 Biomarker phenotype CTD_mouse Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942 2005