Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4282
Gene Symbol: MIF
MIF
0.310 Biomarker phenotype BEFREE MIF/CD74 axis is a target for novel therapies in colon carcinomatosis. 28114961 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.310 GeneticVariation phenotype BEFREE Compared with 673 stage IV patients without MIPC, patients with MIPC had higher EGFR mutation rate (p=0.036); even male smokers had a high EGFR mutation rate (91%). 22523351 2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.310 Biomarker phenotype BEFREE We conclude that peritoneal fibrosis induced by TGF-β1 is dependent on Smad2 signaling and may provide a hospitable environment for carcinomatosis. 22139024 2012
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.310 Biomarker phenotype CTD_human Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942 2005
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.310 Biomarker phenotype CTD_human DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling. 15302576 2004
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.310 AlteredExpression phenotype BEFREE MEK5 may be one of the Stat3-regulated genes and plays its essential roles in oncogenesis mediated by aberrantly activated Stat3 signaling in breast carcinomatosis and malignancies. 15378007 2004
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.310 Therapeutic phenotype CTD_human Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells. 12417722 2002
Entrez Id: 4282
Gene Symbol: MIF
MIF
0.310 Biomarker phenotype CTD_human cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene. 12376462 2002
Entrez Id: 387
Gene Symbol: RHOA
RHOA
0.300 Biomarker phenotype CTD_human Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma. 24816255 2014
Entrez Id: 8626
Gene Symbol: TP63
TP63
0.300 Biomarker phenotype CTD_human Arsenic suppresses cell survival via Pirh2-mediated proteasomal degradation of ΔNp63 protein. 23271742 2013
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
0.300 Biomarker phenotype CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778 2011
Entrez Id: 23643
Gene Symbol: LY96
LY96
0.300 Biomarker phenotype CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778 2011
Entrez Id: 140738
Gene Symbol: TMEM37
TMEM37
0.300 Biomarker phenotype CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049 2011
Entrez Id: 51129
Gene Symbol: ANGPTL4
ANGPTL4
0.300 Biomarker phenotype CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049 2011
Entrez Id: 4692
Gene Symbol: NDN
NDN
0.300 Biomarker phenotype CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049 2011
Entrez Id: 11151
Gene Symbol: CORO1A
CORO1A
0.300 Biomarker phenotype CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049 2011
Entrez Id: 4233
Gene Symbol: MET
MET
0.300 Biomarker phenotype CTD_human HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma. 20661229 2011
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.300 Biomarker phenotype CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778 2011
Entrez Id: 8725
Gene Symbol: URI1
URI1
0.300 Biomarker phenotype CTD_human URI is an oncogene amplified in ovarian cancer cells and is required for their survival. 21397856 2011
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.300 Biomarker phenotype CTD_human Impact of ABCB1 C3435T polymorphism on lymph node regression in multimodality treatment of locally advanced esophageal cancer. 21332314 2011
Entrez Id: 9540
Gene Symbol: TP53I3
TP53I3
0.300 Biomarker phenotype CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049 2011
Entrez Id: 1789
Gene Symbol: DNMT3B
DNMT3B
0.300 Biomarker phenotype CTD_human DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer. 21458988 2011
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
0.300 Biomarker phenotype CTD_human DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer. 21458988 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.300 Biomarker phenotype CTD_human SMAD4--molecular gladiator of the TGF-beta signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene. 20565773 2010
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.300 Biomarker phenotype CTD_human Occupational trichloroethylene exposure and renal carcinoma risk: evidence of genetic susceptibility by reductive metabolism gene variants. 20663906 2010