Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.010 Biomarker disease BEFREE A high index of suspicion and ancillary testing, including P16 immunostaining and molecular genetic testing for HPV, is required to properly diagnose and subclassify HPV-related endocervical adenocarcinoma metastatic to the ovary. 26360235 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.010 GeneticVariation disease BEFREE Sarcomatous transformation of EGFR and TP53 mutation-positive metastatic adenocarcinoma of the lungs, masquerading as a primary pleomorphic sarcoma of the proximal femur. 26045851 2015
Entrez Id: 3309
Gene Symbol: HSPA5
HSPA5
0.010 AlteredExpression disease BEFREE Furthermore, we examined GRP78 expression in a tissue array and found that the GRP78 expression in metastatic adenocarcinoma in lymph nodes tended to be weaker than that in primary colonic adenocarcinoma. 25431258 2015
Entrez Id: 406984
Gene Symbol: MIR200B
MIR200B
0.010 AlteredExpression disease BEFREE Online microRNA database searching revealed that ZEB2 is the top-ranked target gene for hsa-miR141-3p and hsa-miR-200b-3p, prompting us to focus ZEB2 expression in brain metastatic adenocarcinoma. 25270520 2014
Entrez Id: 9839
Gene Symbol: ZEB2
ZEB2
0.010 AlteredExpression disease BEFREE Online microRNA database searching revealed that ZEB2 is the top-ranked target gene for hsa-miR141-3p and hsa-miR-200b-3p, prompting us to focus ZEB2 expression in brain metastatic adenocarcinoma. 25270520 2014
Entrez Id: 54658
Gene Symbol: UGT1A1
UGT1A1
0.010 GeneticVariation disease BEFREE Patients with histologically confirmed metastatic adenocarcinoma of the colon or rectum were enrolled into a UGT1A1 genotype-directed dose-escalation trial of irinotecan plus fixed-dose capecitabine (2,000 mg/m(2)/day). 23595344 2013
Entrez Id: 238
Gene Symbol: ALK
ALK
0.010 GeneticVariation disease BEFREE Here we report the case of a patient with metastatic adenocarcinoma of the lung harboring an ALK gene translocation. 24075124 2013
Entrez Id: 2348
Gene Symbol: FOLR1
FOLR1
0.010 Biomarker disease BEFREE An ongoing phase II, double blind, placebo-controlled study is evaluating farletuzumab in patients with FOLR1 expressing metastatic adenocarcinoma of lung. 23357463 2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.010 GeneticVariation disease BEFREE Patients with mutant KRAS metastatic adenocarcinoma of the colon or rectum refractory to fluoropyrimidine- and oxaliplatin-based chemotherapy were randomized 1 : 1 : 1 to receive intravenous FOLFIRI plus conatumumab 10 mg/kg (Arm A), ganitumab 12 mg/kg (Arm B), or placebo (Arm C) Q2W. 23510984 2013
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.010 Biomarker disease BEFREE Trastuzumab in combination with capecitabine or 5-fluorouracil and cisplatin is approved by the European Medicines Agency for the treatment of patients with human epidermal growth factor receptor 2 (HER2)-positive (immunohistochemistry 3+ or immunohistochemistry 2+/fluorescence in situ hybridization-positive or immunohistochemistry 2+/silver in situ hybridization-positive) metastatic adenocarcinoma of the stomach or gastro-esophageal junction. 22222640 2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.010 Biomarker disease BEFREE We utilized a new anti-MYC antibody coupled with genetically defined control experiments to localize MYC protein within human tissue microarrays consisting of normal, atrophy, PIN, primary adenocarcinoma, and metastatic adenocarcinoma. 18567993 2008
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
0.010 Biomarker disease BEFREE Phase I trial of a recombinant vaccinia virus encoding carcinoembryonic antigen in metastatic adenocarcinoma: comparison of intradermal versus subcutaneous administration. 10499601 1999
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8
0.010 Biomarker disease BEFREE We describe the morphologic findings in order to heighten awareness that CD30+ ALCL may mimic metastatic adenocarcinoma in a body fluid or bronchial brushing and should be considered in the differential diagnosis. 9484639 1998
Entrez Id: 4922
Gene Symbol: NTS
NTS
0.010 Biomarker disease BEFREE This study examines NT secretion, NT receptor and NT-growth responses in androgen-independent prostatic carcinoma (PC3) cells derived from prostate adenocarcinoma metastatic to bone. 9167771 1997
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.010 Biomarker disease BEFREE IL-6 concentration is measured by enzyme-linked immunoadsorbent assay (ELISA) in the ejaculate plasma of healthy men, in primary culture of prostate epithelial cells, in human prostate cancer cell line cultures and SCID mouse xenografts, and in the plasma of 73 men with metastatic adenocarcinoma of the prostate. 7879350 1995