Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2902
Gene Symbol: GRIN1
GRIN1
0.410 Biomarker phenotype HPO
Entrez Id: 9091
Gene Symbol: PIGQ
PIGQ
0.100 GeneticVariation phenotype CLINVAR
Entrez Id: 284111
Gene Symbol: SLC13A5
SLC13A5
0.100 Biomarker phenotype HPO
Entrez Id: 8621
Gene Symbol: CDK13
CDK13
0.100 GeneticVariation phenotype CLINVAR
Entrez Id: 9757
Gene Symbol: KMT2B
KMT2B
0.100 GeneticVariation phenotype CLINVAR
Entrez Id: 8575
Gene Symbol: PRKRA
PRKRA
0.100 Biomarker phenotype HPO
Entrez Id: 84340
Gene Symbol: GFM2
GFM2
0.100 Biomarker phenotype HPO
Entrez Id: 814
Gene Symbol: CAMK4
CAMK4
0.100 GeneticVariation phenotype CLINVAR
Entrez Id: 10522
Gene Symbol: DEAF1
DEAF1
0.100 Biomarker phenotype HPO
Entrez Id: 93210
Gene Symbol: PGAP3
PGAP3
0.100 Biomarker phenotype HPO
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
0.100 CausalMutation phenotype CLINVAR
Entrez Id: 1727
Gene Symbol: CYB5R3
CYB5R3
0.010 Biomarker phenotype BEFREE NADH-diaphorase and cytochrome b5 reductase activities of platelets and leucocytes, as well as erythrocytes, were found to be deficient in a patient with hereditary methaemoglobinaemia associated with moderate mental retardation and non-progressive neurological disturbance, in which hyperactive reflexes and involuntary movements were notable. 6896729 1982
Entrez Id: 1861
Gene Symbol: TOR1A
TOR1A
0.020 Biomarker phenotype BEFREE The MF pattern was present in DYT1 carriers with and without clinical manifestations and persisted in DYT1 dystonia patients in whom involuntary movements were suppressed by sleep. 9749595 1998
Entrez Id: 1356
Gene Symbol: CP
CP
0.310 Biomarker phenotype BEFREE Three sporadic patients (two men and one woman) were examined with involuntary movements and dysarthria associated with abnormal concentrations of serum copper, serum ceruloplasmin, and urinary copper excretion. 11723201 2001
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
0.300 Biomarker phenotype CTD_human Susceptibility to neuroleptic-induced tardive dyskinesia and the T102C polymorphism in the serotonin type 2A receptor. 11526996 2001
Entrez Id: 4051
Gene Symbol: CYP4F3
CYP4F3
0.010 GeneticVariation phenotype BEFREE Schizophrenia patients who carry the dopamine D3gly allele and the cytochrome P 450 17alpha-hydroxylase A2-A2 genotype may be more likely to develop abnormal orofoacial and distal involuntary movements and to be incapacitated by these movements when chronically exposed to classical antipsychotic drugs. 11839369 2002
Entrez Id: 1356
Gene Symbol: CP
CP
0.310 Biomarker phenotype CTD_human Aceruloplasminemia, an inherited disorder of iron metabolism. 12572680 2003
Entrez Id: 1861
Gene Symbol: TOR1A
TOR1A
0.020 Biomarker phenotype BEFREE We conclude that aberrant opioid transmission is unlikely to be present in DYT1-PTD and altered opioid transmission is not a common mechanism underlying all disorders of involuntary movement. 15390064 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.300 Biomarker phenotype CTD_human Genotype and smoking history affect risk of levodopa-induced dyskinesias in Parkinson's disease. 16435402 2006
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
0.300 Biomarker phenotype CTD_human Genotype and smoking history affect risk of levodopa-induced dyskinesias in Parkinson's disease. 16435402 2006
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
0.010 Biomarker phenotype BEFREE We report on a patient with HD, whose involuntary movements and psychiatric symptoms were clinically improved with perospirone, a second-generation antipsychotic agent with antagonistic effects on serotonin 5-HT(2A) and dopamine D(2) (D(2)) receptors, as well as a unique agonistic effect on serotonin 5-HT(1A) (5-HT(1A)) receptors. 16887250 2007
Entrez Id: 84152
Gene Symbol: PPP1R1B
PPP1R1B
0.300 Therapeutic phenotype CTD_human Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors. 20682746 2010
Entrez Id: 3631
Gene Symbol: INPP4A
INPP4A
0.010 Biomarker phenotype BEFREE Notably, Inpp4a(-/-) mice show severe involuntary movement disorders. 20463662 2010
Entrez Id: 5173
Gene Symbol: PDYN
PDYN
0.300 Biomarker phenotype CTD_human Imaging mass spectrometry reveals elevated nigral levels of dynorphin neuropeptides in L-DOPA-induced dyskinesia in rat model of Parkinson's disease. 21984936 2011
Entrez Id: 55145
Gene Symbol: THAP1
THAP1
0.020 Biomarker phenotype BEFREE Thanatos-associated [THAP] domain-containing apoptosis-associated protein 1 (THAP1) is a DNA-binding protein that has been recently associated with DYT6 dystonia, a hereditary movement disorder involving sustained, involuntary muscle contractions. 21752024 2011