Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2533
Gene Symbol: FYB1
0.010 AlteredExpression disease BEFREE Importantly, the overexpression of FYB was correlated with breast cancer metastasis. 30712460 2020
Entrez Id: 8420
Gene Symbol: SNHG3
0.010 Biomarker disease BEFREE The findings of this study show that SNHG3 functions as an oncogene in breast cancer and promotes breast cancer cell proliferation and invasion by regulating the miR-384/HDGF axis. 31586299 2020
Entrez Id: 100874365
Gene Symbol: HOXC-AS3
0.010 Biomarker disease BEFREE HOXC-AS3 could be a novel therapeutic target for breast cancer therapeutics. 31797701 2020
Entrez Id: 105377871
Gene Symbol: LOC105377871
0.010 GeneticVariation disease BEFREE Results showed that in northwest Chinese Han population, SNP rs17530068 (LOC105377871) increases the risk of breast cancer and SNP rs4784227 (CASC16) promotes lymph node metastasis in breast cancer patients. 31655495 2020
Entrez Id: 100500843
Gene Symbol: MIR3922
0.010 Biomarker disease BEFREE Our results demonstrated that miR-3922-5p was a direct target of HOXC-AS3, and PPP1R1A was a target of miR-3922-5p in breast cancer.<b>Conclusions:</b> The novel lncRNA HOXC-AS3 acts as a miR-3922-5p sponge to upregulate PPP1R1A protein expression, and thus results in promoting breast cancer metastasis. 31797701 2020
Entrez Id: 90668
Gene Symbol: CARMIL3
0.010 AlteredExpression disease BEFREE Moreover, molecular pathway enrichment analysis reveals that lack of CARMIL3 leads to loss of cell adhesions and low CARMIL3 expression in breast cancer patient specimens is implicated in epithelial-mesenchymal transition. 31694931 2020
Entrez Id: 100616288
Gene Symbol: MIR4665
0.010 Biomarker disease BEFREE Receiver operating characteristic curve analyses indicated that miR‑150‑5p [area under the curve (AUC)=0.705, upregulated], miR‑576‑3p (AUC=0.691, upregulated), miR‑4665‑5p (AUC=0.681, upregulated) were able to distinguish breast cancer patients with recurrence from those without recurrence. 31746410 2020
Entrez Id: 6440
Gene Symbol: SFTPC
0.010 Biomarker disease BEFREE Here, we demonstrated that breast cancer (MDA-MB-231) cell-derived exosomes (231-Exo) could be specifically internalized by non-small cell lung cancer cells via a specific interaction between overexpressed integrin β4 (on exosomes) and surfactant protein C (SPC) on the cancer cells. 31833519 2020
Entrez Id: 283624
Gene Symbol: LINC00641
0.010 AlteredExpression disease BEFREE LINC00641 acts as a competitive endogenous RNA to sponge miR-194-5p. miR-194-5p level was higher in BC tissues and cells compared with normal-adjacent tissues and normal breast epithelial cell. miR-194-5p expression was negatively correlated with LINC00641 expression in BC tissues. miR-194-5p overexpression reversed the effects of LINC00641 on cell proliferation, cycle, apoptosis, migration, as well as invasion. 31490021 2020
Entrez Id: 3122
Gene Symbol: HLA-DRA
0.010 AlteredExpression disease BEFREE Moreover, elevated HLA-DRA and FYB levels were associated with breast cancer recurrence. 30712460 2020
Entrez Id: 100506394
Gene Symbol: GAS6-DT
0.010 Biomarker disease BEFREE These results revealed that GAS6-AS2 sponges miR-493 to enhance the malignant characteristics of BC in vitro and in vivo by increasing FUT4 expression. 31839366 2020
Entrez Id: 261729
Gene Symbol: STEAP2
0.010 AlteredExpression disease BEFREE The low expression of STEAP2 was detected in breast cancer tissues, which was associated with malignant phenotype and poor prognosis of breast cancer. 31696760 2020
Entrez Id: 54879
Gene Symbol: ST7L
0.010 Biomarker disease BEFREE Taken together, our results demonstrate that ST7L exerts antitumor function in breast cancer associated with the suppression of Wnt/β-catenin signalling, suggesting ST7L as a potential therapeutic target for breast cancer. 31429477 2020
Entrez Id: 80853
Gene Symbol: KDM7A
0.010 Biomarker disease BEFREE In conclusion, KDM7A promotes cancer stem cell maintenance and apoptosis inhibition in breast cancer. 31236965 2020
Entrez Id: 11343
Gene Symbol: MGLL
0.010 Biomarker disease BEFREE GPD1 and MAGL might be promising tissue-based protein biomarkers with a predictive potential for BC. 31467232 2020
Entrez Id: 3948
Gene Symbol: LDHC
0.010 AlteredExpression disease BEFREE Survival analysis showed that LDH-C4 expression negatively correlated with BC prognosis. 31794764 2020
Entrez Id: 649
Gene Symbol: BMP1
0.010 Biomarker disease BEFREE In the present study, surface doses within the target area and contralateral breast (CLB) received during conventional treatment of carcinoma breast are evaluate and compared for treatment on two different beam energies, i.e., Co-60 γ-ray and 6 MV X-ray beams with thermoluminescent dosimeter, LiF:Mg, Ti (TLD-100). 31603107 2020
Entrez Id: 6927
Gene Symbol: HNF1A
0.010 AlteredExpression disease BEFREE For example, AF1q has been shown to interact with T-cell Factor 7 (TCF7; also known as TCF1) from the Wnt/β-catenin pathway resulting in the transcriptional activation of the CD44 and the enhancement of breast cancer metastasis. 31541685 2020
Entrez Id: 55361
Gene Symbol: PI4K2A
0.010 Biomarker disease BEFREE We observed that PKR and PI4K2A play significant prognostic roles in breast cancer patients. 31554935 2020
Entrez Id: 1002
Gene Symbol: CDH4
0.010 GeneticVariation disease BEFREE Bioinformatics prediction and experimental validation of a novel microRNA: hsa-miR-B43 within human CDH4 gene with a potential metastasis-related function in breast cancer. 31489987 2020
Entrez Id: 51652
Gene Symbol: CHMP3
0.010 AlteredExpression disease BEFREE A higher level of CHMP3 gene predicted a better 3- and 5-year survival outcome of patients with BRCA. 31541468 2020
Entrez Id: 121643
Gene Symbol: FOXN4
0.010 AlteredExpression disease BEFREE In addition, ectopically expression of FOXN4 led to the decreased cell proliferation, reduced colony formation and metastatic abilities (EMT, migration and invasion) in breast cancer cell lines. 31430519 2020
Entrez Id: 114796
Gene Symbol: PSMG3-AS1
0.010 Biomarker disease BEFREE In conclusion, the results of the present study identified a novel lncRNA PSMG3‑AS1, which serves as a sponge for miR‑143‑3p in the pathogenesis of breast cancer. 31661146 2020
Entrez Id: 100861402
Gene Symbol: CERS6-AS1
0.010 Biomarker disease BEFREE Taken together, these evidences suggested that CERS6-AS1 promoted the progression of BC by binding to IGF2BP3 and thus enhancing the stability of CERS6 mRNA, providing a new underlying therapeutic target for BC to improve prognosis. 31701672 2020
Entrez Id: 84324
Gene Symbol: SARNP
0.010 AlteredExpression disease BEFREE However, the role of SARNP in mRNA splicing and export and in the progression of breast cancer, especially of TNBC, remains unknown. 31313837 2020