Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7432
Gene Symbol: VIP
0.010 GeneticVariation phenotype BEFREE A Phase IV, Randomized, Double-Blind, Placebo-Controlled Crossover Study of the Effects of Ustekinumab on Vascular Inflammation in Psoriasis (the VIP-U Trial). 31326395 2020
Entrez Id: 2740
Gene Symbol: GLP1R
0.010 Biomarker phenotype BEFREE GLP-1R activation attenuates cardiovascular complications of arterial hypertension by reduction of vascular inflammation through selective actions requiring the endothelial but not the myeloid cell GLP-1R. 31747801 2020
Entrez Id: 59272
Gene Symbol: ACE2
0.010 Biomarker phenotype BEFREE Mechanisms pertaining to IRW as an ACE2 activator in vivo include enhanced endothelium-dependent vasorelaxation and reduced vascular inflammation. 30913349 2019
Entrez Id: 51441
Gene Symbol: YTHDF2
0.010 Biomarker phenotype BEFREE YTHDF2 silenced in human HCC cells or ablated in mouse hepatocytes provoked inflammation, vascular reconstruction and metastatic progression. 31735169 2019
Entrez Id: 26291
Gene Symbol: FGF21
0.010 Biomarker phenotype BEFREE On the other hand, FGF21 therapy significantly improves lipid profiles, and reduces vascular inflammation and oxidative stress in atherosclerosis related diseases. 30879171 2019
Entrez Id: 93978
Gene Symbol: CLEC6A
0.010 Biomarker phenotype BEFREE Our findings demonstrate that Dectin-2-mediated induction of CCL2 production by macrophages resident in the aortic root and coronary arteries initiates vascular inflammation in a model of Kawasaki disease, suggesting an important role for the innate immune system in initiating vasculitis. 31169521 2019
Entrez Id: 133522
Gene Symbol: PPARGC1B
0.010 Biomarker phenotype BEFREE β-aminoisobutyric acid protects against vascular inflammation through PGC-1β-induced antioxidative properties. 31277947 2019
Entrez Id: 574447
Gene Symbol: MIR146B
0.010 Biomarker phenotype BEFREE A PI3K inhibitor decreased the effect of microRNA-146b on vascular inflammation and apoptosis following myocardial infarction. 30679990 2019
Entrez Id: 8751
Gene Symbol: ADAM15
0.010 Biomarker phenotype BEFREE The absence of ADAM15 at low shear stress or static conditions may therefore lead to increased endothelial damage and promote vascular inflammation. 31271758 2019
Entrez Id: 54567
Gene Symbol: DLL4
0.010 Biomarker phenotype BEFREE These results suggest that novel crosstalk between OATP2B1 and Dll4-Notch signaling in macrophages mediates indoxyl sulfate-induced vascular inflammation in CKD. 30586693 2019
Entrez Id: 10105
Gene Symbol: PPIF
0.010 Biomarker phenotype BEFREE We adopted CypD KO mouse and their littermate controls to observe the effects of CypD deficiency on aortic mitochondrial functions and vascular inflammation. 30554656 2019
Entrez Id: 857
Gene Symbol: CAV1
0.010 Biomarker phenotype BEFREE Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation. 31154825 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
0.010 Biomarker phenotype BEFREE A PI3K inhibitor decreased the effect of microRNA-146b on vascular inflammation and apoptosis following myocardial infarction. 30679990 2019
Entrez Id: 10135
Gene Symbol: NAMPT
0.010 AlteredExpression phenotype BEFREE High visfatin / NAMPT(nicotinamide phosphoribosyltransferase) plasma levels may promote vascular inflammation and atherosclerotic plaque destabilization and have been evaluated as a marker for identifying stages of essential hypertension. 31022738 2019
Entrez Id: 799
Gene Symbol: CALCR
0.010 GeneticVariation phenotype BEFREE The subset of patients with HPV-positive tumors experienced the greatest increases in vascular inflammation due to CRT. 31109689 2019
Entrez Id: 26273
Gene Symbol: FBXO3
0.010 Biomarker phenotype BEFREE Thus, FBXO3 potentiates vascular inflammation and atherosclerosis that can be effectively mitigated by a small molecule inhibitor. 30448480 2019
Entrez Id: 8517
Gene Symbol: IKBKG
0.010 Biomarker phenotype BEFREE MiR-181a-5p and miR-181a-3p mimetics retard atherosclerosis progression through blocking NF-κB activation and vascular inflammation by targeting TAB2 and NEMO, respectively. 31064980 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
0.010 Biomarker phenotype BEFREE A PI3K inhibitor decreased the effect of microRNA-146b on vascular inflammation and apoptosis following myocardial infarction. 30679990 2019
Entrez Id: 350
Gene Symbol: APOH
0.010 Biomarker phenotype BEFREE Our results provided the first evidence supporting the important role of activated B cell-derived anti-β2GPI IgG in HHcy-aggravated chronic vascular inflammation and AAA formation. 31782769 2019
Entrez Id: 3572
Gene Symbol: IL6ST
0.010 Biomarker phenotype BEFREE Thus, in conclusion, these results indicate that IL-6 trans-signaling is an important mediator of inflammation, apoptosis and barrier disruptive effects in the retinal endothelial cells and inhibition of the IL-6 trans-signaling pathway using sgp130-Fc attenuates vascular inflammation and endothelial barrier disruption. 30240585 2019
Entrez Id: 574501
Gene Symbol: MIR499A
0.010 Biomarker phenotype BEFREE This study implies that miR-499 may serve as a potential target for the treatment of the surged vascular inflammation post-AMI. 31270949 2019
Entrez Id: 8744
Gene Symbol: TNFSF9
0.010 Biomarker phenotype BEFREE Various studies demonstrate that CD137 (TNFRSF9, 4-1BB) promotes atherosclerosis and vascular inflammation in experimental models via interactions with the CD137 ligand (CD137L). 30778712 2019
Entrez Id: 2896
Gene Symbol: GRN
0.010 Biomarker phenotype BEFREE In conclusion, progranulin exerted protective effects on the function and morphology of photoreceptors in a hypoxic environment, and could reduce retinal vascular inflammation, through inhibition of the TLR4‑NOX4 pathway. 30431085 2019
Entrez Id: 710
Gene Symbol: SERPING1
0.010 Biomarker phenotype BEFREE Plasma protein C1 inhibitor (C1INH) is an inhibitor of vascular inflammation that is induced by activation of the kallikrein-kinin system (KKS) and the complement system. 30882931 2019
Entrez Id: 27086
Gene Symbol: FOXP1
0.010 AlteredExpression phenotype BEFREE Simvastatin upregulated the reduced expression of Klf2 and Foxp1 in atherosusceptible vascular endothelium and alleviated vascular inflammation contributing to its inhibitory effect in atherosclerosis. 31318658 2019