Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23583
Gene Symbol: SMUG1
0.030 Biomarker phenotype BEFREE <sup>18</sup>F-FDG PET imaging conditions optimized for vascular inflammation imaging lead to an improved quantification through an increase in the quantified vascular tracer uptake and decrease in blood-pool background activity. 31388966 2019
Entrez Id: 6750
Gene Symbol: SST
0.010 Biomarker phenotype BEFREE (Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography [VISION]; NCT02021188). 28385306 2017
Entrez Id: 246
Gene Symbol: ALOX15
0.020 Biomarker phenotype BEFREE 15-Lipoxygenase-1 (ALOX15) has been implicated in vascular inflammation and disease. 27594770 2016
Entrez Id: 1361
Gene Symbol: CPB2
0.010 Biomarker phenotype BEFREE Thrombin activatable fibrinolysis inhibitor, a potential regulator of vascular inflammation. 14525995 2003
Entrez Id: 183
Gene Symbol: AGT
0.100 Biomarker phenotype BEFREE Angiotensin II (AngII) is implicated in atherogenesis by activating the vascular inflammation system, mainly through monocyte chemotaxis. 14739122 2004
Entrez Id: 5175
Gene Symbol: PECAM1
0.030 Biomarker phenotype BEFREE Platelet-endothelial cell adhesion molecule-1 (PECAM-1) mediates the transendothelial migration of circulating leukocytes, a characteristic change in vascular inflammation leading to atherosclerotic plaque development. 15589815 2004
Entrez Id: 5175
Gene Symbol: PECAM1
0.030 Biomarker phenotype BEFREE Platelet endothelial cell adhesion molecule-1 (PECAM-1) plays a key role in the transendothelial migration of circulating leukocytes (diapedesis) during vascular inflammation. 15756041 2005
Entrez Id: 183
Gene Symbol: AGT
0.100 Biomarker phenotype BEFREE Angiotensin II has been implicated in the pathogenesis of vascular inflammation in various organs. 16545368 2006
Entrez Id: 5340
Gene Symbol: PLG
0.020 Biomarker phenotype BEFREE Plasminogen activator inhibitor (PAI)-1 in vascular inflammation and thrombosis. 17485272 2007
Entrez Id: 4306
Gene Symbol: NR3C2
0.030 Biomarker phenotype BEFREE Mineralocorticoid receptor activation has been demonstrated to result in increased tissue oxidative stress and vascular inflammation, while recent studies provide evidence for changes in tissue oxidative stress, in turn regulating mineralocorticoid receptor activation by alternate ligands. 18277151 2008
Entrez Id: 5468
Gene Symbol: PPARG
0.010 Biomarker phenotype BEFREE Peroxisome proliferator-activated receptor gamma (PPARgamma) agonists have been shown to prevent vascular inflammation and leakage in an experimental model of diabetes. 18806296 2009
Entrez Id: 3164
Gene Symbol: NR4A1
0.020 AlteredExpression phenotype BEFREE Nur77 is highly expressed in vascular endothelial cells (ECs) and plays a role in the regulation of cell proliferation and angiogenesis; its role in vascular inflammation, however, remains unknown. 19213954 2009
Entrez Id: 9365
Gene Symbol: KL
0.010 Biomarker phenotype BEFREE Klotho-disrupted mice exhibit atherosclerosis and endothelial dysfunction, which led us to investigate the effect of the Klotho protein on vascular inflammation, particularly adhesion molecule expression. 19367378 2009
Entrez Id: 284
Gene Symbol: ANGPT1
0.010 Biomarker phenotype BEFREE Angiopoietin-1 is a vascular strengthening factor during vascular development and a protective factor for pathological vascular inflammation and leakage. 20378606 2010
Entrez Id: 5919
Gene Symbol: RARRES2
0.020 Biomarker phenotype BEFREE Chemerin as a mediator between obesity and vascular inflammation in children. 22438234 2012
Entrez Id: 9370
Gene Symbol: ADIPOQ
0.040 Biomarker phenotype BEFREE Adiponectin is the most abundantly secreted protein from adipose tissue and has been shown to decrease hepatic glucose production, increase fatty acid oxidation in liver and skeletal muscle, and decrease vascular inflammation. 23017722 2012
Entrez Id: 85463
Gene Symbol: ZC3H12C
0.010 Biomarker phenotype BEFREE Zc3h12c inhibits vascular inflammation by repressing NF-κB activation and pro-inflammatory gene expression in endothelial cells. 23360436 2013
Entrez Id: 6915
Gene Symbol: TBXA2R
0.010 Biomarker phenotype BEFREE Thromboxane A2 receptor (TPr) has been reported to trigger vascular inflammation. 23539217 2013
Entrez Id: 6749
Gene Symbol: SSRP1
0.010 Biomarker phenotype BEFREE High mobility group box protein 1 (HMGB1) and receptor for the advanced glycation end product (RAGE) play pivotal roles in vascular inflammation and atherosclerosis. 23564080 2013
Entrez Id: 6283
Gene Symbol: S100A12
0.040 Biomarker phenotype BEFREE S100A12 induces vascular inflammation contributing to the development of atherosclerosis. 23921255 2013
Entrez Id: 28999
Gene Symbol: KLF15
0.020 Biomarker phenotype BEFREE Kruppel-like factor 15 is critical for vascular inflammation. 23999430 2013
Entrez Id: 9368
Gene Symbol: SLC9A3R1
0.010 Biomarker phenotype BEFREE Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-κB (NF-κB): a feed-forward loop for systemic and vascular inflammation. 24196963 2013
Entrez Id: 183
Gene Symbol: AGT
0.100 Biomarker phenotype BEFREE Angiotensin II (Ang II) stimulates vascular inflammation, oxidative stress, and formation and rupture of intracranial aneurysms in mice. 24799613 2014
Entrez Id: 7408
Gene Symbol: VASP
0.010 Biomarker phenotype BEFREE Vasodilator-stimulated phosphoprotein protects against vascular inflammation and insulin resistance. 25117404 2014
Entrez Id: 2103
Gene Symbol: ESRRB
0.010 Biomarker phenotype BEFREE Orphan nuclear receptor Nur77 is potently induced in macrophages by diverse stimuli, suggesting that it is of importance in vascular inflammation resulting in atherosclerosis, but whether Nur77 induction is detrimental or protective is unclear. 26768365 2016