Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 953
Gene Symbol: ENTPD1
0.010 Biomarker group BEFREE Moreover, tumor-infiltrating CD73<sup>+</sup> Teffs failed to express inhibitory immune checkpoints, suggesting that CD73 might be selected under pressure from immune checkpoint blockade therapy and thus may represent a nonredundant target for restoring antitumor immunity.<b>Significance:</b> Polyfunctional CD73<sup>+</sup> T-cell effectors lacking other immune checkpoints are selectively targeted by CD39 overexpressing Tregs that dominate the breast tumor environment.<i></i>. 29559470 2018