Disease: Nicotine Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
CHRNB2 P17787 cholinergic receptor nicotinic beta 2 subunit Ion channel 7.3E-04 0.617 0.308
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CHRNB4 P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 0.14 0.644 0.423
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
LINC02210-CRHR1 P34998 LINC02210-CRHR1 readthrough 0.570 0.692
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808