Disease: Mixed anxiety and depressive disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
FZD4 Q9ULV1 frizzled class receptor 4 G-protein coupled receptor 0.97 0.490 0.923
GPR151 Q8TDV0 G protein-coupled receptor 151 G-protein coupled receptor 3.2E-08 0.530 0.923
GPR166P G protein-coupled receptor 166 pseudogene 0.531 0.923
GPRC6A Q5T6X5 G protein-coupled receptor class C group 6 member A G-protein coupled receptor 5.6E-17 0.526 0.923
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
LGR6 Q9HBX8 leucine rich repeat containing G protein-coupled receptor 6 G-protein coupled receptor 2.9E-06 0.502 0.923
LINC02210-CRHR1 P34998 LINC02210-CRHR1 readthrough 0.570 0.692
LPAR3 Q9UBY5 lysophosphatidic acid receptor 3 G-protein coupled receptor 0.68 0.509 0.923
MRGPRX1 Q96LB2 MAS related GPR family member X1 G-protein coupled receptor 0.531 0.923
MRGPRX3 Q96LB0 MAS related GPR family member X3 G-protein coupled receptor 0.529 0.923
MRGPRX4 Q96LA9 MAS related GPR family member X4 G-protein coupled receptor 0.531 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846