| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.720 | GeneticVariation | BEFREE | Recently, a novel locus at chromosome 6p25 (rs12204590, near <i>FOXF2</i>) associated with an increased risk of stroke in European populations was identified. | 29163794 | 2017 |
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0.720 | GeneticVariation | GWASCAT | The rs12204590 stroke risk allele was also associated with increased MRI-defined burden of white matter hyperintensity-a marker of cerebral small vessel disease-in stroke-free adults (n=21 079; p=0·0025). | 27068588 | 2016 |
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|
0.720 | GeneticVariation | BEFREE | We replicated seven of eight known loci associated with risk for ischaemic stroke, and identified a novel locus at chromosome 6p25 (rs12204590, near FOXF2) associated with risk of all-stroke (odds ratio [OR] 1·08, 95% CI 1·05-1·12, p=1·48 × 10(-8); minor allele frequency 21%). | 27068588 | 2016 |