| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
T | 0.700 | CausalMutation | CLINVAR | The PI3K pathway as drug target in human cancer. | 20085938 | 2010 |
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|
T | 0.700 | CausalMutation | CLINVAR | Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. | 20453058 | 2010 |
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|
T | 0.700 | CausalMutation | CLINVAR | Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. | 11504908 | 2001 |
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|
T | 0.700 | CausalMutation | CLINVAR | Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. | 10555148 | 1999 |