Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs185229225
rs185229225
0.700 GeneticVariation GWASCAT Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence. 27047539

2016

dbSNP: rs121913322
rs121913322
0.700 GeneticVariation UNIPROT

dbSNP: rs121964872
rs121964872
0.700 GeneticVariation UNIPROT

dbSNP: rs80357522
rs80357522
CT 0.700 GeneticVariation CLINVAR

dbSNP: rs80357678
rs80357678
C 0.700 GeneticVariation CLINVAR

dbSNP: rs864622149
rs864622149
T 0.700 GeneticVariation CLINVAR

dbSNP: rs3218536
rs3218536
0.070 GeneticVariation BEFREE The obtained results indicate that XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms may be positively associated with the incidence of ovarian carcinoma in the population of Polish women. 26801223

2016

dbSNP: rs3218536
rs3218536
0.070 GeneticVariation BEFREE In conclusion, this meta-analysis indicates that XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms may not be associated with the risk of OC. 27863412

2016

dbSNP: rs3218536
rs3218536
0.070 GeneticVariation BEFREE Overall, a significant association was found between the Arg188His polymorphism and ovarian cancer risk when all studies were pooled into the meta-analysis (Arg/Arg vs His/His: OR = 1.85, 95%CI = 1.15-3.00; Arg/Arg vs Arg/His: OR = 1.17, 95%CI = 1.03-1.32; dominant model: OR = 0.84, 95%CI = 0.74-0.95; recessive model: OR = 1.69, 95%CI = 1.05-2.70). 26400309

2015

dbSNP: rs1217691063
rs1217691063
0.070 GeneticVariation BEFREE The C677T polymorphism of the MTHFR gene is associated with the susceptibility of ovarian cancer in Asian population, suggesting that TT genotype may serve as a risk factor of ovarian cancer among Asian but not Caucasians. 24720627

2014

dbSNP: rs3218536
rs3218536
0.070 GeneticVariation BEFREE The current meta-analysis indicated that the Arg188His polymorphism in the XRCC2 gene might be a risk factor for ovarian cancer. 24414483

2014

dbSNP: rs3218536
rs3218536
0.070 GeneticVariation BEFREE Interestingly, XRCC2 G>A (rs3218536) polymorphism might reduce the risk of ovarian cancer. 24599673

2014

dbSNP: rs1217691063
rs1217691063
0.070 GeneticVariation BEFREE This meta-analysis supports an association between MTHFR C677T polymorphism and ovarian cancer risk, and there might be a race-specific effect in this association. 23329275

2013

dbSNP: rs1217691063
rs1217691063
0.070 GeneticVariation BEFREE Our analysis indicated neither folate intake nor MTHFR C677T polymorphism is related to altered susceptibility of ovarian cancer. 24129496

2013

dbSNP: rs3218536
rs3218536
0.070 GeneticVariation BEFREE The aim of the present study was to evaluate the role of SNPs in three genes, XRCC2 (R188H), ERCC2 (K751Q) and CDKN1B (V109G) which are with moderate risk for ovarian cancer susceptibility in Egyptian women. 23277402

2013

dbSNP: rs1217691063
rs1217691063
0.070 GeneticVariation BEFREE In conclusion, we observed that the MTHFR C677T polymorphism is associated with the susceptibility and survival of ovarian cancer in Chinese population. 22524826

2012

dbSNP: rs1217691063
rs1217691063
0.070 GeneticVariation BEFREE In conclusion, the results of this meta-analysis indicate that the MTHFR C677T and A1298C polymorphisms are not associated with ovarian cancer risk, especially in Caucasians. 22810649

2012

dbSNP: rs1217691063
rs1217691063
0.070 GeneticVariation BEFREE MTHFR C677T polymorphism and ovarian cancer risk: a meta-analysis. 23098496

2012

dbSNP: rs1217691063
rs1217691063
0.070 GeneticVariation BEFREE Overall, we observed no association between either SNP and ovarian cancer risk (pooled C677T p(trend)=0.59 and A1298C p(trend)=0.58). 20817226

2010

dbSNP: rs3218536
rs3218536
0.070 GeneticVariation BEFREE The XRCC2 R188H polymorphism was associated with a modest reduction in EOC risk: OR for heterozygotes was 0.8 (95% confidence interval [CI] = 0.7-1.0) and for rare homozygotes 0.3 (0.1-0.9). 15924337

2005

dbSNP: rs1695
rs1695
0.060 GeneticVariation BEFREE <i>GSTP1</i> rs1695 is associated with both hematological toxicity and prognosis of ovarian cancer treated with paclitaxel plus carboplatin combination chemotherapy: a comprehensive analysis using targeted resequencing of 100 pharmacogenes. 30038720

2018

dbSNP: rs1695
rs1695
0.060 GeneticVariation BEFREE This study aimed to evaluate whether GSTM1 and GSTT1 (presents or nulls), GSTP1 c.313A>G and NQO2 c.-102A>C polymorphisms, involved in xenobiotic detoxification pathways, alter outcomes of epithelial ovarian cancer (EOC) patients. 27586145

2016

dbSNP: rs1695
rs1695
0.060 GeneticVariation BEFREE Large epidemiological studies with the combination of GSTM1 null, GSTT1 null and GSTP1 Ile105Val polymorphisms and more specific histological subtypes of OC are needed to prove our findings. 25124586

2014

dbSNP: rs1695
rs1695
0.060 GeneticVariation BEFREE We tested in this study whether the GSTM1, GSTT1 and GSTP1 Ile105Val polymorphisms alter the risk of EOC. 22960333

2012

dbSNP: rs1695
rs1695
0.060 GeneticVariation BEFREE Several studies have examined whether GST polymorphisms (GSTM1 null/present genotype, GSTT1 null/present genotype, and GSTP1 Ile105Val) represent risk factors for ovarian cancer, as they all may denote reduced enzyme activity. 20966642

2010