G6PD, glucose-6-phosphate dehydrogenase, 2539

N. diseases: 410; N. variants: 66
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 AlteredExpression disease BEFREE We measured G6PD activity spectrophotometrically in four groups of 15 parietal somatosensory association cortex [Brodmann area (BA) 7] tissue samples (N = 60) from individuals with bipolar disorder (BPD); nonpsychotic unipolar major depression (UPD); schizophrenia (SCZ), and controls without psychiatric illness (CON). 30875545 2019
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 Biomarker disease PSYGENET Various other protein products of genes associated with bipolar disorder either bind to or are affected by phosphatidyl-inositol phosphate products of this pathway (ADBRK2, HIP1R, KCNQ2, RGS4, WFS1), are associated with its constituent elements (BCR, DUSP6, FAT, GNAZ) or are downstream targets of this signalling cascade (DPYSL2, DRD3, GAD1, G6PD, GCH1, KCNQ2, NOS3, SLC6A3, SLC6A4, SST, TH, TIMELESS). 17239488 2007
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 GeneticVariation disease BEFREE Maternal inheritance of manic depression in hemizygotes for the G6PD-Mediterranean mutation. Indirect evidence for Xq28 transmission in Sardinia. 10412184 1999
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 Biomarker disease PSYGENET Maternal inheritance of manic depression in hemizygotes for the G6PD-Mediterranean mutation. Indirect evidence for Xq28 transmission in Sardinia. 10412184 1999
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 Biomarker disease PSYGENET Evidence of a predisposing locus to bipolar disorder on Xq24-q27.1 in an extended Finnish pedigree. 9132265 1995
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 Biomarker disease PSYGENET Manic-depressive illness and linkage reanalysis in the Xq27-Xq28 region of chromosome X. 7760986 1995
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 Biomarker disease PSYGENET X-chromosome markers and manic-depressive illness. Rejection of linkage to Xq28 in nine bipolar pedigrees. 2322087 1990
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.330 GeneticVariation disease BEFREE (c) Reported linkages of bipolar illness to colorblind and G6PD loci are compatible with known map distances between X-chromosome loci. 6454708 1981