AMY2A, amylase alpha 2A, 279

N. diseases: 21; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0362046
Disease: Prediabetes syndrome
Prediabetes syndrome 		0.010 AlteredExpression disease BEFREE These animals are also a source of pancreatic α-amylase inhibitors, which have the ability to control the glucose level in the blood and can be used for the treatment of prediabetes and type 2 diabetes mellitus. 31546678 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.010 Biomarker disease BEFREE We demonstrated that AMY2A, a possible TSG, is frequently silenced in GC deletion 1p21.1. 20428766 2010
CUI: C0751783
Disease: Lafora Disease
Lafora Disease 		0.010 Biomarker disease BEFREE We report studies on the efficacy and CNS delivery of VAL-0417, an antibody-enzyme fusion composed of the 3E10 hFab and human pancreatic α-amylase, in a mouse model of LD. 31329461 2019
CUI: C3495814
Disease: Fulminant type 1 diabetes mellitus
Fulminant type 1 diabetes mellitus 		0.010 Biomarker disease BEFREE Seven out of 10 clones were amylase alpha-2A, the autoantibody to which was specifically detected in sera from patients with AIP and fulminant type 1 diabetes (FT1DM) [T. Endo, S. Takizawa, S. Tanaka, M. Takahashi, H. Fujii, T. Kamisawa, T. Kobayashi, Amylase alpha-2A autoantibodies: novel marker of autoimmune pancreatitis and fulminant type 1 diabetes mellitus, Diabetes 58 (2009) 732-737]. 19520060 2009
CUI: C0030305
Disease: Pancreatitis
Pancreatitis 		0.010 Biomarker disease LHGDN Amylase alpha-2A autoantibodies: novel marker of autoimmune pancreatitis and fulminant type 1 diabetes. 19001184 2009