Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.040 AlteredExpression disease BEFREE These animals are also a source of pancreatic α-amylase inhibitors, which have the ability to control the glucose level in the blood and can be used for the treatment of prediabetes and type 2 diabetes mellitus. 31546678 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.040 Biomarker disease BEFREE The acylated flavonol glycoside montbretin A (MbA) and its precursor myricetin 3-<i>O</i>-(6'-<i>O</i>-caffeoyl)-glucosyl rhamnoside (mini-MbA) are potent inhibitors of human pancreatic α-amylase and are being developed as drug candidates to treat type-2 diabetes. 29967287 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.040 Biomarker disease BEFREE We found potent pancreatic α-amylase inhibition in Astilbe thunbergii root extract (AT) and confirmed that AT treatment in a T2DM rat model reduces post-starch administration blood glucose levels. 28743229 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.040 Biomarker disease BEFREE Structures of human pancreatic α-amylase in complex with acarviostatins: Implications for drug design against type II diabetes. 21111049 2011