Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker disease BEFREE Lewis (Le)-associated antigens are carbohydrates that are related biochemically to the ABO blood groups, and may have a role in Helicobacter pylori adherence. 16456898 2006
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker disease BEFREE Effect of Helicobacter pylori Eradication and ABO Genotype on Gastric Cancer Development. 27191536 2016
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker disease BEFREE Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori. 26764597 2016
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker disease BEFREE BabA is a Helicobacter pylori cell surface adhesin, which binds to the ABO/Le(b) histo-blood group antigens (Le(b)) and serves as a virulence factor. 27318698 2016
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker disease BEFREE The Helicobacter pylori babA gene encodes an outer membrane protein that mediates binding to fucosylated ABH antigens of the ABO blood group. 20123715 2010
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker disease BEFREE For instance, ABO status affects the infectivity of certain strains of Helicobacter pylori and Noroviruses as well as the sequestration and rosetting of red blood cells infected with Plasmodium falciparum. 21945157 2012
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 Biomarker disease BEFREE The BabA adhesin mediates high-affinity binding of Helicobacter pylori to the ABO blood group antigen-glycosylated gastric mucosa. 28279347 2017
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 GeneticVariation disease BEFREE We showed that SNPs in the ABO gene, predictive of ABO blood groups, are associated with risk of advanced precancerous gastric lesions in individuals infected with Hp, but the assessment of the risk is strictly dependent on cagA status. 23319424 2013
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 GeneticVariation disease BEFREE Other identified associations are human immunodeficiency virus infection, ABO blood group polymorphisms, hepatitis B virus, and Helicobacter pylori. 25726048 2015
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 GeneticVariation disease BEFREE Although several studies have investigated the association between ABO blood type and risk of gastric cancer (GC), atrophic gastritis (AG), and Helicobacter pylori (HP) infection, no study has investigated these associations by using ABO genotype. 21680535 2011
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
0.100 GeneticVariation disease BEFREE ABO blood serotype A is known to be associated with risk of gastric cancer (GC), but little is known how ABO alleles and the fucosyltransferase (FUT) enzymes and genes which are involved in Lewis antigen formation [and in Helicobacter pylori (H. pylori) binding and pathogenicity] may be related to GC risk in a European population. 24947433 2015