PRCP, prolylcarboxypeptidase, 5547

N. diseases: 68; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0349204
Disease: Nonorganic psychosis
Nonorganic psychosis
0.010 Biomarker disease BEFREE Accumulating evidence shows that mGluR5 antagonists by themselves do not necessarily disrupt pre-pulse inhibition (PPI), but can exacerbate disruption of PPI caused by MK-801 and PCP, while positive modulation of this receptor has beneficial effects on these models of psychosis. 18063347 2008