C1QBP, complement C1q binding protein, 708

N. diseases: 111; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 AlteredExpression disease BEFREE C1QBP is highly expressed in breast cancer and positively correlates with MRE11 expression, and the inhibition of C1QBP enhances tumor regression with chemotherapy. 31353207 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 GeneticVariation disease BEFREE This study aims to evaluate the potential association of single nucleotide polymorphisms (SNPs) of HABP1 with breast cancer in northern Chinese women. 28108744 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 AlteredExpression disease BEFREE Furthermore, C1QBP was observed to be overexpressed in breast cancer tissues, and its expression level was closely linked with distant metastasis and TNM stages. 23924515 2013
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 Biomarker disease CTD_human An integrative approach to identify YB-1-interacting proteins required for cisplatin resistance in MCF7 and MDA-MB-231 breast cancer cells. 21466612 2011
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 Biomarker disease BEFREE HABP1 might be an independent predictive factor for breast cancer prognosis and up-regulation of HABP1 might play an important role in the metastasis of breast cancer. 19565630 2009
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.350 AlteredExpression disease BEFREE Since p52, p51 and p33 correlate with uPA levels, these forms of Ets-1 may play a role in breast cancer metastasis. 15365563 2004