PRDM2, PR/SET domain 2, 7799

N. diseases: 115; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 Biomarker disease BEFREE We studied associations of genetic variants of folate metabolizing enzymes (MTHFR, MTR, and MTRR), DNA methyltransferase DNMT3b, and histone methyltransferases (EHMT1, EHMT2, and PRDM2), with colorectal cancers, with or without the CpG island methylator phenotype (CIMP), MLH1 hypermethylation, or microsatellite instability. 19843671 2009
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 Biomarker disease BEFREE Clinicopathological significance of microsatellite instability and mutated RIZ in colorectal cancer. 14760116 2004
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 Biomarker disease BEFREE These results suggest that RIZ1 may be useful in gene therapy of MSI(+) colorectal cancers. 11280725 2001
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 AlteredExpression disease BEFREE Four of eleven microsatellite-unstable colorectal cancer cell lines, three of which had frameshifts, showed reduced or absent mRNA expression of RIZ1. 10688904 2000