PRDM2, PR/SET domain 2, 7799

N. diseases: 115; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 Biomarker disease BEFREE In this study, we showed that RIZ1 mRNA expression level was elevated in stage IV of eight different types of cancer (stage III for prostate cancer), indicating that RIZ1 might play an important role in tumor metastasis, and the PR domain alone possessed anticancer activity. 21369371 2011
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 AlteredExpression disease BEFREE Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2. 19746436 2009
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 PosttranslationalModification disease BEFREE DNA methylation of RIZ1 tended to be present more frequently in PCa specimens with a high Gleason score (16/30, 53.3%) than in those with a low Gleason score (4/17, 23.5%); however, this tendency was not statistically significant (P = 0.0675). 17052263 2007