CBR1, carbonyl reductase 1, 873

N. diseases: 100; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.040 AlteredExpression disease BEFREE Second, we detected 3.0-fold (p<0.0001) induction of CBR1 mRNA and 1.5-fold (p<0.01) induction of CBR1 protein levels in cells of the human lung cancer cell line A549 incubated with 2.5 μM B[a]P for 24h. 22531821 2012
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.040 GeneticVariation disease BEFREE One SNP in CBR1 (rs2835267) was significantly associated with overall risk of lung cancer, but did not pass multiple testing adjustment (OR: 0.76 95% CI: 0.58-0.99, P = 0.048, FDR P = 0.20). 24976539 2015
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.040 Biomarker disease BEFREE 15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancer. 18593902 2008
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.040 Biomarker disease BEFREE A CBR framework with gradient boosting based feature selection for lung cancer subtype classification. 28527352 2017