CBR1, carbonyl reductase 1, 873

N. diseases: 100; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.310 GeneticVariation group BEFREE Among individuals carrying the variant A allele (CBR1:GA/AA and/or CBR3:GA/AA), exposure to low- to moderate-dose anthracyclines (1 to 250 mg/m(2)) did not increase the risk of cardiomyopathy. 22124095 2012
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.310 Biomarker group CTD_human Human carbonyl reductase overexpression in the heart advances the development of doxorubicin-induced cardiotoxicity in transgenic mice. 11016643 2000