GDF15, growth differentiation factor 15, 9518

N. diseases: 389; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.370 Biomarker group LHGDN Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells. 12941831 2003
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.370 GeneticVariation group LHGDN H6D polymorphism in macrophage-inhibitory cytokine-1 gene associated with prostate cancer. 15316060 2004
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.370 Biomarker group LHGDN Three new serum markers for prostate cancer detection within a percent free PSA-based artificial neural network. 16388506 2006
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.370 Biomarker group LHGDN Prostate derived factor in human prostate cancer cells: gene induction by vitamin D via a p53-dependent mechanism and inhibition of prostate cancer cell growth. 16741990 2006
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.370 GeneticVariation group LHGDN Macrophage inhibitory cytokine-1 H6D polymorphism, prostate cancer risk, and survival. 16775185 2006
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.370 Biomarker group CTD_human Macrophage inhibitory cytokine-1 H6D polymorphism, prostate cancer risk, and survival. 16775185 2006
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.370 AlteredExpression group LHGDN In mice with xenografted prostate tumors, elevated MIC-1 levels were also associated with marked weight, fat and lean tissue loss that was mediated by decreased food intake and was reversed by administration of antibody to MIC-1. 17982462 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.370 AlteredExpression group BEFREE Studies with transgenic mice expressing human NAG-1 demonstrated that the expression of NAG-1 inhibits the development of intestinal tumors and prostate tumors in animal models. 23220538 2013
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.370 Biomarker group CTD_human Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis. 23996089 2014