MED12, mediator complex subunit 12, 9968

N. diseases: 340; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders
0.420 GeneticVariation group BEFREE Second, a balanced polymorphism in the C terminus opposite-paired domain, a key motif in the MED12-mediated transcriptional repression of Wnt signaling, has been associated with increased risk for psychosis. 17716226 2007
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders
0.420 Biomarker group BEFREE In an effort to determine whether other allelic polymorphisms in this gene exist and may potentially contribute to increased susceptibility to neuropsychiatric illness, we have performed single stranded conformational polymorphism (SSCP) analysis of all 45 exons and each of the two potential promoter regions of HOPA using DNA from a panel of patients with psychosis. 14582143 2003
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders
0.420 Biomarker group PSYGENET In an effort to determine whether other allelic polymorphisms in this gene exist and may potentially contribute to increased susceptibility to neuropsychiatric illness, we have performed single stranded conformational polymorphism (SSCP) analysis of all 45 exons and each of the two potential promoter regions of HOPA using DNA from a panel of patients with psychosis. 14582143 2003
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders
0.420 Biomarker group HPO